Concepedia

Subsite Architecture

Subsite Architecture is an academic construct that specifies the structural and functional organization of localized binding or catalytic regions within an enzyme's active site, distinguished by its focus on discrete subsites that collectively enable substrate recognition, orientation, and catalytic specificity.

98

Publications

6.2K

Citations

481

Authors

170

Institutions

Publications per year

2017–2026

11

Parents

Publications

98

Binding of small molecules to an adaptive protein–protein interface

Michelle R. Arkin, Mike Randal, Warren L. DeLano et al. · Proceedings of the National Academy of Sciences · 2003 · 380 citations

, , +17

SARS-CoV 3CL protease cleaves its C-terminal autoprocessing site by novel subsite cooperativity

Tomonari Muramatsu, Chie Takemoto, YongTae Kim et al. · Proceedings of the National Academy of Sciences · 2016 · 304 citations · Full text

, , +17

Subsite Mapping of the Human Pancreatic α-Amylase Active Site through Structural, Kinetic, and Mutagenesis Techniques<sup>,</sup>

Gary D. Brayer, Gary Sidhu, R. Maurus et al. · Biochemistry · 2000 · 261 citations

, , +17

Structure of the <i>Aspergillus oryzae</i> α-Amylase Complexed with the Inhibitor Acarbose at 2.0 Å Resolution<sup>,</sup>

A.M. Brzozowski, G.J. Davies · Biochemistry · 1997 · 221 citations

, , +17

Bacterial promoter architecture: subsite structure of UP elements and interactions with the carboxy-terminal domain of the RNA polymerase alpha subunit

Shawn T. Estrem, Wilma Ross, Tamás Gaál et al. · Genes & Development · 1999 · 211 citations · Full text

, , +17

1–5 of 98

Authors

481

  1. MA
    María A. Juliano

    Universidade Federal de São Paulo, Brazil

    4 publications · 124 citations

    4

    h-index

  2. LK
    Lili Kandra

    University of Debrecen, Hungary

    3 publications · 93 citations

    3

    h-index

  3. SG
    Stephen G. Withers

    University of British Columbia, Canada

    3 publications · 531 citations

    3

    h-index

  4. GD
    G.J. Davies

    University of York, United Kingdom

    3 publications · 355 citations

    3

    h-index

  5. GD
    Gary D. Brayer

    University of British Columbia, Canada

    3 publications · 531 citations

    3

    h-index

1–5 of 481

Institutions

170

  1. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    24 publications

    812 citations

  2. University of British Columbia

    Vancouver, Canada

    4 h-index

    26 publications

    4.3K citations

  3. University of York

    York, United Kingdom

    3 h-index

    8 publications

    922 citations

  4. University of Copenhagen

    Copenhagen, Denmark

    3 h-index

    10 publications

    607 citations

  5. University of Debrecen

    Debrecen, Hungary

    3 h-index

    9 publications

    309 citations

  6. Novozymes (Denmark)

    Copenhagen, Denmark

    3 h-index

    4 publications

    269 citations

  7. University of East Anglia

    Norwich, United Kingdom

    3 h-index

    11 publications

    421 citations

  8. Texas A&M University

    College Station, United States

    3 h-index

    10 publications

    1.3K citations

1–8 of 170

Venues

  1. Biochemistry

    20 publications · 1.9K citations

    19

    h-index

  2. Journal of Biological Chemistry

    JBC · 11 publications · 977 citations

    11

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 999 citations

    9

    h-index

  4. 7

    h-index

  5. FEBS Letters

    5 publications · 222 citations

    5

    h-index

1–5