Concepedia

Subclonal Dynamics

Subclonal Dynamics is a computational oncology framework that models the temporal evolution and heterogeneous composition of genetically distinct subpopulations within tumors by integrating longitudinal genomic data to infer clonal selection, expansion, and extinction processes over time.

64

Publications

5.2K

Citations

819

Authors

293

Institutions

Publications per year

2017–2026

46

Parents

Publications

64

Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity

Andriy Marusyk, Doris P. Tabassum, Philipp M. Altrock et al. · Nature · 2014 · 615 citations · Full text

, , +16

TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data

Gavin Ha, Andrew Roth, Jaswinder Khattra et al. · Genome Research · 2014 · 429 citations · Full text

, , +17

Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts

Jeffrey J. Quinn, Matthew G. Jones, Ross A. Okimoto et al. · Science · 2021 · 315 citations · Full text

, , +17

Breast tumours maintain a reservoir of subclonal diversity during expansion

Darlan Conterno Minussi, Michael D. Nicholson, Hanghui Ye et al. · Nature · 2021 · 288 citations · Full text

, , +14

Epidemiology Of Chronic Pseudomonas aeruginosa Infections In Cystic Fibrosis

Ute Römling, B. Fiedler, Dietmar Grothues et al. · The Journal of Infectious Diseases · 1994 · 252 citations

, , +17

1–5 of 64

Authors

819

  1. AS
    Andrea Sottoriva

    Institute of Cancer Research, United Kingdom

    5 publications · 371 citations

    5

    h-index

  2. DS
    Darryl Shibata

    University of Southern California, United States

    4 publications · 258 citations

    4

    h-index

  3. GC
    Giulio Caravagna

    Institute of Cancer Research, United Kingdom

    4 publications · 351 citations

    4

    h-index

  4. TA
    Trevor A. Graham

    Queen Mary University of London, United Kingdom

    4 publications · 351 citations

    4

    h-index

  5. GD
    George D. Cresswell

    Institute of Cancer Research, United Kingdom

    4 publications · 351 citations

    4

    h-index

1–5 of 819

Institutions

293

  1. University College London

    London, United Kingdom

    7 h-index

    28 publications

    2.3K citations

  2. Institute of Cancer Research

    London, United Kingdom

    7 h-index

    56 publications

    5.4K citations

  3. Harvard University

    Cambridge, United States

    6 h-index

    24 publications

    5.6K citations

  4. Queen Mary University of London

    London, United Kingdom

    5 h-index

    42 publications

    2.9K citations

  5. University of California, San Francisco

    San Francisco, United States

    5 h-index

    23 publications

    3.3K citations

  6. Genomics (United Kingdom)

    Oxford, United Kingdom

    5 h-index

    30 publications

    2.4K citations

  7. University of Southern California

    Los Angeles, United States

    5 h-index

    12 publications

    537 citations

  8. The Francis Crick Institute

    London, United Kingdom

    4 h-index

    27 publications

    2.8K citations

1–8 of 293

Venues

  1. Nature Communications

    9 publications · 717 citations

    9

    h-index

  2. Leukemia

    3 publications · 245 citations

    3

    h-index

  3. Nature

    3 publications · 1.1K citations

    3

    h-index

  4. International Journal of Cancer

    3 publications · 116 citations

    3

    h-index

  5. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 3 publications · 74 citations

    3

    h-index

1–5