Concepedia

Structural Epitope Mapping

Structural Epitope Mapping is a structural biology method that identifies the precise three-dimensional atomic interface on an antigen recognized by an antibody or immune receptor, distinguishing it from linear epitope mapping by its reliance on high-resolution spatial data from techniques such as X-ray crystallography or cryo-electron microscopy.

150

Publications

8K

Citations

931

Authors

341

Institutions

Publications per year

2017–2026

29

Parents

Publications

150

The Biological Activity of Human CD20 Monoclonal Antibodies Is Linked to Unique Epitopes on CD20

Jessica L. Teeling, Wendy J.M. Mackus, Luus Wiegman et al. · The Journal of Immunology · 2006 · 604 citations

, , +17

Comparison of a Structural and a Functional Epitope

Brian C. Cunningham, James A. Wells · Journal of Molecular Biology · 1993 · 517 citations

, , +12

Mapping Epitope Structure and Activity: From One-Dimensional Prediction to Four-Dimensional Description of Antigenic Specificity

Marc H.V. Van Regenmortel · Methods · 1996 · 252 citations

, , +17

Mapping of the p53 and mdm-2 Interaction Domains

Jiandong Chen, Vincent Maréchal, Arnold J. Levine · Molecular and Cellular Biology · 1993 · 244 citations

, , +12

The molecular basis for allergen cross-reactivity: crystal structure and IgE-epitope mapping of birch pollen profilin

Tanja Ball, Nicole M. Mahoney, Rudolf Valenta et al. · Structure · 1997 · 228 citations · Full text

, , +16

1–5 of 150

Authors

931

  1. KD
    K. Dane Wittrup

    Massachusetts Institute of Technology, United States

    3 publications · 290 citations

    3

    h-index

  2. SM
    Sergei M. Danilov

    University of Illinois Chicago, United States

    2 publications · 72 citations

    2

    h-index

  3. TB
    Thomas Bourquard

    Centre National de la Recherche Scientifique, France

    2 publications · 53 citations

    2

    h-index

  4. JL
    Jing Lin

    Icahn School of Medicine at Mount Sinai, United States

    2 publications · 75 citations

    2

    h-index

  5. MH
    Matan Halfon

    Hebrew University of Jerusalem, Israel

    2 publications · 99 citations

    2

    h-index

1–5 of 931

Institutions

341

  1. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    36 publications

    1.2K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    9 publications

    375 citations

  3. Vrije Universiteit Brussel

    Brussels, Belgium

    4 h-index

    8 publications

    692 citations

  4. Emory University

    Atlanta, United States

    4 h-index

    14 publications

    562 citations

  5. Northwestern University

    Evanston, United States

    4 h-index

    20 publications

    442 citations

  6. Scripps Research Institute

    San Diego, United States

    3 h-index

    8 publications

    178 citations

  7. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    14 publications

    1.2K citations

  8. Monash University

    Melbourne, Australia

    3 h-index

    17 publications

    600 citations

1–8 of 341

Venues

  1. Journal of Biological Chemistry

    JBC · 11 publications · 610 citations

    11

    h-index

  2. Journal of Molecular Biology

    JMB · 12 publications · 1.3K citations

    11

    h-index

  3. Molecular Immunology

    7 publications · 170 citations

    7

    h-index

  4. Biochemistry

    6 publications · 222 citations

    6

    h-index

  5. The Journal of Immunology

    JI · 6 publications · 836 citations

    6

    h-index

1–5