Concepedia

Structural Determinants Of Specificity

Structural Determinants of Specificity is a theoretical construct in structural biology that identifies the precise molecular features and interactions within biomolecular complexes that confer selective binding or functional discrimination among interacting partners.

257

Publications

15.1K

Citations

1.1K

Authors

351

Institutions

Publications per year

2017–2026

22

Parents

Publications

257

Molecular discrimination of structurally equivalent Lys 63‐linked and linear polyubiquitin chains

David Komander, Francisca E. Reyes‐Turcu, Julien Licchesi et al. · EMBO Reports · 2009 · 572 citations · Full text

, , +7

Preformed Structural Elements Feature in Partner Recognition by Intrinsically Unstructured Proteins

Mónika Fuxreiter, István Simon, Péter Friedrich et al. · Journal of Molecular Biology · 2004 · 512 citations

, , +16

Thromboxanes: Selective Biosynthesis and Distinct Biological Properties

Philip Needleman, Mark S. Minkes, Amiram Raz · Science · 1976 · 390 citations

, , +17

Local Structural Elements in the Mostly Unstructured Transcriptional Activation Domain of Human p53

Hyun Lee, K. Hun Mok, Ranjith Muhandiram et al. · Journal of Biological Chemistry · 2000 · 339 citations · Full text

, , +14

Structural Determinants for Selective Recognition of a Lys48-Linked Polyubiquitin Chain by a UBA Domain

Ranjani Varadan, Michael Assfalg, Shahri Raasi et al. · Molecular Cell · 2005 · 242 citations · Full text

, , +16

1–5 of 257

Authors

1.1K

  1. CR
    Charles R. Dawson

    Columbia University, United States

    3 publications · 77 citations

    3

    h-index

  2. MJ
    M J Peach

    University of Virginia, United States

    3 publications · 140 citations

    3

    h-index

  3. AP
    A. Peter Kurtz

    Columbia University, United States

    3 publications · 77 citations

    3

    h-index

  4. CW
    Carl W. Porter

    Roswell Park Comprehensive Cancer Center, United States

    3 publications · 241 citations

    3

    h-index

  5. HB
    Harold Baer

    Center for Biologics Evaluation and Research, United States

    3 publications · 77 citations

    3

    h-index

1–5 of 1.1K

Institutions

351

  1. National Institutes of Health

    Bethesda, United States

    13 h-index

    43 publications

    1.8K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    39 publications

    1.5K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    17 publications

    2K citations

  4. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    5 h-index

    14 publications

    1.1K citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    4 h-index

    12 publications

    1.1K citations

  6. Johns Hopkins University

    Baltimore, United States

    4 h-index

    10 publications

    1.4K citations

  7. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    4 h-index

    10 publications

    241 citations

  8. University of California, San Francisco

    San Francisco, United States

    4 h-index

    10 publications

    1.4K citations

1–8 of 351

Venues

  1. Journal of Biological Chemistry

    JBC · 24 publications · 1.6K citations

    21

    h-index

  2. Biochemistry

    13 publications · 887 citations

    13

    h-index

  3. Journal of Molecular Biology

    JMB · 8 publications · 902 citations

    8

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 503 citations

    7

    h-index

  5. PubMed

    Repository · 7 publications · 236 citations

    7

    h-index

1–5