Concepedia

Stacking In G-quadruplexes

Stacking in G-Quadruplexes is a structural phenomenon in nucleic acid chemistry characterized by the preferential spatial arrangement and π-orbital overlap of guanine-rich tetrads within G-quadruplex architectures that stabilizes the higher-order folding through non-covalent interactions distinct from Watson-Crick base pairing.

219

Publications

12.3K

Citations

844

Authors

303

Institutions

Publications per year

2017–2026

73

Variants

Base Stacking In G-quadruplexes

Parents

Publications

219

Base-stacking and base-pairing contributions to helix stability: thermodynamics of double-helix formation with CCGG, CCGGp, CCGGAp, ACCGGp, CCGGUp, and ACCGGUp

Matthew Petersheim, Douglas H. Turner · Biochemistry · 1983 · 505 citations

, , +17

Interactions of TMPyP4 and TMPyP2 with Quadruplex DNA. Structural Basis for the Differential Effects on Telomerase Inhibition

Frank Xiaoguang Han, Richard T. Wheelhouse, Laurence H. Hurley · Journal of the American Chemical Society · 1999 · 336 citations

, , +17

Structural Basis for Binding of Porphyrin to Human Telomeres<sup>,</sup>

Gary N. Parkinson, Ragini Ghosh, Stephen Neidle · Biochemistry · 2007 · 310 citations

, , +17

Platinum(II) Complexes with Dipyridophenazine Ligands as Human Telomerase Inhibitors and Luminescent Probes for G-Quadruplex DNA

Dik‐Lung Ma, Chi‐Ming Che, Siu‐Cheong Yan · Journal of the American Chemical Society · 2008 · 288 citations

, , +15

Structure of Propeller-Type Parallel-Stranded RNA G-Quadruplexes, Formed by Human Telomeric RNA Sequences in K<sup>+</sup> Solution

Herry Martadinata, Anh Tuân Phan · Journal of the American Chemical Society · 2009 · 241 citations

, , +15

1–5 of 219

Authors

844

  1. AT
    Anh Tuân Phan

    Nanyang Technological University, Singapore

    16 publications · 1.6K citations

    16

    h-index

  2. JP
    Janez Plavec

    National Institute of Chemistry, Slovenia

    13 publications · 622 citations

    13

    h-index

  3. JM
    Jean‐Louis Mergny

    Inserm, France

    10 publications · 301 citations

    10

    h-index

  4. VG
    Valérie Gabelica

    University of Liège, Belgium

    9 publications · 727 citations

    9

    h-index

  5. BH
    Brahim Heddi

    Nanyang Technological University, Singapore

    8 publications · 806 citations

    8

    h-index

1–5 of 844

Institutions

303

  1. Centre National de la Recherche Scientifique

    Paris, France

    21 h-index

    83 publications

    3.6K citations

  2. Nanyang Technological University

    Singapore, Singapore

    17 h-index

    62 publications

    5.4K citations

  3. Inserm

    Paris, France

    14 h-index

    55 publications

    1.9K citations

  4. National Institute of Chemistry

    Ljubljana, Slovenia

    13 h-index

    41 publications

    2K citations

  5. University of Ljubljana

    Ljubljana, Slovenia

    12 h-index

    21 publications

    957 citations

  6. EN-FIST Centre of Excellence (Slovenia)

    Ljubljana, Slovenia

    11 h-index

    18 publications

    862 citations

  7. Chinese Academy of Sciences

    Beijing, China

    10 h-index

    42 publications

    1.9K citations

  8. Université de Bordeaux

    Bordeaux, France

    10 h-index

    35 publications

    1.4K citations

1–8 of 303

Venues

  1. Nucleic Acids Research

    27 publications · 1.9K citations

    27

    h-index

  2. Journal of the American Chemical Society

    JACS · 24 publications · 2.7K citations

    23

    h-index

  3. Biochemistry

    14 publications · 1.6K citations

    14

    h-index

  4. Chemistry - A European Journal

    15 publications · 520 citations

    13

    h-index

  5. The Journal of Physical Chemistry B

    11 publications · 461 citations

    11

    h-index

1–5