Richard T. Wheelhouse

Cationic Porphyrins as Telomerase Inhibitors:  the Interaction of Tetra-(<i>N</i>-methyl-4-pyridyl)porphine with Quadruplex DNA

Richard T. Wheelhouse, Daekyu Sun, Haiyong Han et al. · Journal of the American Chemical Society · 1998 · 443 citations

Quadruplex Dna, Pharmaceutical Science, Bioorganic Chemistry +19

NMR and Molecular Modeling Investigation of the Mechanism of Activation of the Antitumor Drug Temozolomide and Its Interaction with DNA

B.J. Denny, Richard T. Wheelhouse, Malcolm F. G. Stevens et al. · Biochemistry · 1994 · 437 citations

Drug Target, Bioorganic Chemistry, Molecular Biology +19

Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells.

Elżbieta Izbicka, Richard T. Wheelhouse, Éric Raymond et al. · PubMed · 1999 · 368 citations

Chemoprevention Strategy, Cationic Porphyrins, Telomerase Activity +18

Interactions of TMPyP4 and TMPyP2 with Quadruplex DNA. Structural Basis for the Differential Effects on Telomerase Inhibition

Frank Xiaoguang Han, Richard T. Wheelhouse, Laurence H. Hurley · Journal of the American Chemical Society · 1999 · 334 citations

Quadruplex Dna, Dna Analysis, Molecular Biology +16

Quadruplex-Interactive Agents as Telomerase Inhibitors:  Synthesis of Porphyrins and Structure−Activity Relationship for the Inhibition of Telomerase

Dong‐Fang Shi, Richard T. Wheelhouse, Daekyu Sun et al. · Journal of Medicinal Chemistry · 2001 · 247 citations · Full text