Concepedia

Stabilization Against Denaturation

Stabilization Against Denaturation is a methodological strategy in enzymology that preserves the native conformation of enzymes under destabilizing conditions by specifically counteracting structural unfolding or aggregation, thereby maintaining catalytic functionality.

34

Publications

2K

Citations

119

Authors

51

Institutions

Publications per year

2017–2026

5

Parents

Publications

34

Pro-sequence of subtilisin can guide the refolding of denatured subtilisin in an intermolecular process

Xueli Zhu, Yoshiji Ohta, Frank Jordan et al. · Nature · 1989 · 348 citations

, , +13

Cycloamylose as an efficient artificial chaperone for protein refolding

Sachiko Machida, Setsuko Ogawa, Takeshi Takaha et al. · FEBS Letters · 2000 · 196 citations · Full text

, , +17

Importance of the structural zinc atom for the stability of yeast alcohol dehydrogenase

E Magonet, P Hayen, Dominique Delforge et al. · Biochemical Journal · 1992 · 139 citations · Full text

, , +17

Strategy for Stabilizing Enzymes Part One: Increasing Stability of Enzymes via their Multi-Point Interaction with a Support

Vadim V. Mozhaev, N. S. Melik‐Nubarov, Mariya V. Sergeeva et al. · Biocatalysis · 1990 · 131 citations

, , +17

The principles of enzyme stabilization

Karel Martínek, Alexander M. Klibanov, Victor S. Goldmacher et al. · Biochimica et Biophysica Acta (BBA) - Enzymology · 1977 · 114 citations

, , +12

1–5 of 34

Authors

119

  1. KM
    Karel Martínek

    Lomonosov Moscow State University, Russia

    4 publications · 377 citations

    4

    h-index

  2. VV
    Vadim V. Mozhaev

    Lomonosov Moscow State University, Russia

    2 publications · 245 citations

    2

    h-index

  3. AM
    Alexander M. Klibanov

    Massachusetts Institute of Technology, United States

    2 publications · 186 citations

    2

    h-index

  4. TK
    Tomonori Kurokáwa

    Hiroshima University, Japan

    1 publications · 11 citations

    1

    h-index

  5. GP
    Guillermo Picó

    National University of Rosario, Argentina

    1 publications · 18 citations

    1

    h-index

1–5 of 119

Institutions

51

  1. Johns Hopkins University

    Baltimore, United States

    2 h-index

    4 publications

    164 citations

  2. Lomonosov Moscow State University

    Moscow, Russia

    2 h-index

    3 publications

    322 citations

  3. Moscow State University

    Dushanbe, Tajikistan

    2 h-index

    8 publications

    786 citations

  4. Biotechnology Institute

    Washington D.C., United States

    1 h-index

    4 publications

    280 citations

  5. Institut de Biologie Structurale

    Grenoble, France

    1 h-index

    2 publications

    214 citations

  6. University of Naples Federico II

    Naples, Italy

    1 h-index

    3 publications

    81 citations

  7. ITMO University

    St Petersburg, Russia

    1 h-index

    2 publications

    24 citations

  8. Tel Aviv University

    Tel Aviv, Israel

    1 h-index

    3 publications

    102 citations

1–8 of 51

Venues

  1. Biochemical Journal

    BJ · 3 publications · 207 citations

    3

    h-index

  2. Biochemical and Biophysical Research Communications

    BBRC · 2 publications · 49 citations

    2

    h-index

  3. Enzyme and Microbial Technology

    2 publications · 62 citations

    2

    h-index

  4. Biochemistry

    2 publications · 82 citations

    2

    h-index

  5. 2

    h-index

1–5