Concepedia

Spinal Pain Modulation

Spinal Pain Modulation is a neurophysiological mechanism within the dorsal horn of the spinal cord that selectively attenuates or facilitates nociceptive signals through synaptic inhibition or excitation, distinguishing it from supraspinal pain modulation by its localized, segmental integration of sensory input and descending control.

885

Publications

50K

Citations

3.1K

Authors

904

Institutions

Publications per year

2017–2026

125

Parents

Publications

885

Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain

Jeffrey A. M. Coull, Dominic Boudreau, Karine Bachand et al. · Nature · 2003 · 1.1K citations

, , +17

Identification of Spinal Circuits Transmitting and Gating Mechanical Pain

Bo Duan, Longzhen Cheng, Steeve Bourane et al. · Cell · 2014 · 587 citations · Full text

, , +14

Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain

Anna K. Clark, Ping K. Yip, John Grist et al. · Proceedings of the National Academy of Sciences · 2007 · 481 citations · Full text

, , +17

Direct evidence that spinal serotonin and noradrenaline terminals mediate the spinal antinociceptive effects of morphine in the periaqueductal gray

Tony L. Yaksh · Brain Research · 1979 · 481 citations

, , +17

Reversal of pathological pain through specific spinal GABAA receptor subtypes

Julia Knabl, Robert Witschi, Katharina M. Hösl et al. · Nature · 2008 · 429 citations

, , +14

1–5 of 885

Authors

3.1K

  1. TL
    Tony L. Yaksh

    University of California San Diego, United States

    20 publications · 2.3K citations

    19

    h-index

  2. AH
    Anthony H. Dickenson

    University College London, United Kingdom

    20 publications · 1.1K citations

    17

    h-index

  3. AP
    Antti Pertovaara

    University of Helsinki, Finland

    13 publications · 543 citations

    12

    h-index

  4. YG
    Yun Guan

    Johns Hopkins University, United States

    11 publications · 813 citations

    11

    h-index

  5. HU
    Hanns Ulrich Zeilhofer

    University of Zurich, Switzerland

    12 publications · 1.2K citations

    11

    h-index

1–5 of 3.1K

Institutions

904

  1. University College London

    London, United Kingdom

    21 h-index

    81 publications

    4.9K citations

  2. Inserm

    Paris, France

    20 h-index

    76 publications

    4.6K citations

  3. Karolinska Institutet

    Stockholm, Sweden

    18 h-index

    63 publications

    4.8K citations

  4. University of Iowa

    Iowa City, United States

    17 h-index

    38 publications

    3.2K citations

  5. University of California San Diego

    San Diego, United States

    17 h-index

    66 publications

    4.6K citations

  6. Johns Hopkins University

    Baltimore, United States

    17 h-index

    117 publications

    8.4K citations

  7. University of Minnesota

    Minneapolis, United States

    16 h-index

    33 publications

    2K citations

  8. McGill University

    Montreal, Canada

    15 h-index

    33 publications

    4.9K citations

1–8 of 904

Venues

  1. Brain Research

    102 publications · 6.6K citations

    47

    h-index

  2. Neuroscience

    62 publications · 3.2K citations

    40

    h-index

  3. Pain

    58 publications · 3.5K citations

    36

    h-index

  4. European Journal of Pharmacology

    EJP · 52 publications · 2.6K citations

    28

    h-index

  5. Neuroscience Letters

    61 publications · 3K citations

    28

    h-index

1–5