Direct evidence that spinal serotonin and noradrenaline terminals mediate the spinal antinociceptive effects of morphine in the periaqueductal gray

Chronic catheterization of the spinal subarachnoid space

Tony L. Yaksh, Thomas A. Rudy · Physiology & Behavior · 1976 · 2.2K citations

Medicine, Neurological Surgery, Neurosurgery +12

Systematic examination in the rat of brain sites sensitive to the direct application of morphine: Observation of differential effects within the periaqueductal gray

Tony L. Yaksh, Joseph C. Yeung, Thomas A. Rudy · Brain Research · 1976 · 606 citations

Medicine, Neuroscience, Pharmacology +17

Studies on the direct spinal action of narcotics in the production of analgesia in the rat.

T L Yaksh, Thomas A. Rudy · Journal of Pharmacology and Experimental Therapeutics · 1977 · 554 citations

Medicine, Anesthesiology, Pharmacology +12

Nucleus raphe magnus inhibition of spinal cord dorsal horn neurons

Howard L. Fields, Allan I. Basbaum, Charles H. Clanton et al. · Brain Research · 1977 · 479 citations

Life Sciences, Neurobiology, Neuroscience +14

Morphine analgesia: Blockade by raphe magnus lesions

Herbert K. Proudfit, Edmund G. Anderson · Brain Research · 1975 · 355 citations

Nursing, Anesthesiology, Pain Management +7