Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus

Qin Liu, Zongxiang Tang, Lenka Surdenikova, +12

Cell

Molecular NeuroscienceNeurophysiologyMedicineSynaptic TransmissionPhysiology +11

A subpopulation of nociceptors specifically linked to itch

Liang Han, Chao Ma, Qin Liu, +14

Nature Neuroscience

AllergyHealth SciencesNeuroanatomyPain MedicineNeuropathic Pain +7

Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

Rebecca P. Seal, Xidao Wang, Yun Guan, +4

Nature

MechanobiologySoft Tissue InjuryEngineeringMuscle InjuryBiomechanics +3

Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain

Shouan Zhu, Jianxi Zhu, Gehua Zhen, +25

Journal of Clinical Investigation

Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain

Yu Shin Kim, Michael Anderson, Kyoungsook Park, +13

Neuron

Pain SyndromeHealth SciencesPain MedicineNeuroanatomyMedicine +8

Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis

Hao Chen, Bo Hu, Xiao Lv, +19

Nature Communications

SclerostinPeripheral NervesCellular PhysiologyOsteoporosisOrthopaedic Surgery +17

Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors

Wei Xiong, Tanxing Cui, Kejun Cheng, +7

The Journal of Experimental Medicine

Pain DisordersPain MedicineNeuropathic PainMolecular PainCannabinoid Pharmacology +20

Tyrosine Phosphorylation of the NR2B Subunit of the NMDA Receptor in the Spinal Cord during the Development and Maintenance of Inflammatory Hyperalgesia

Wei Guo, Shiping Zou, Yun Guan, +4

Journal of Neuroscience

TRP Vanilloid 2 Knock-Out Mice Are Susceptible to Perinatal Lethality But Display Normal Thermal and Mechanical Nociception

Una Park, Nisha Vastani, Yun Guan, +3

Journal of Neuroscience

Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain

Hao-Jui Weng, Kush Patel, Nathaniel A. Jeske, +12

Neuron

Pain SyndromeHealth SciencesPain MedicineImmunologyTrpa1-trpv1 Complex +7