Somatic Variant Analysis is a computational and bioinformatic approach that identifies and characterizes acquired genetic alterations in tumor cells by distinguishing them from germline variants, thereby enabling the detection of cancer-specific mutations with implications for diagnosis, prognosis, and targeted therapy.
335
Publications
38.8K
Citations
4.3K
Authors
1.1K
Institutions
Publications per year
2017–2026
178
Publications
335
Maftools: efficient and comprehensive analysis of somatic variants in cancer
Anand Mayakonda, De‐Chen Lin, Yassen Assenov et al. · Genome Research · 2018 · 5.4K citations · Full text
Strelka: accurate somatic small-variant calling from sequenced tumor–normal sample pairs
Christopher T. Saunders, Wendy S.W. Wong, Sajani Swamy et al. · Bioinformatics · 2012 · 1.8K citations · Full text
Life Sciences, Genetics, Oncology +17
The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website
Sally Bamford, Elisabeth Dawson, Simon Forbes et al. · British Journal of Cancer · 2004 · 1.3K citations · Full text
Life Sciences, Genetics, Oncology +16
MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia
Steven P. Treon, Lian Xu, Guang Yang et al. · New England Journal of Medicine · 2012 · 1.3K citations · Full text
1–5 of 335
Authors
4.3K
- MR
8
h-index
- GG
8
h-index
- AG
7
h-index
- PAP. Andrew Futreal
The University of Texas MD Anderson Cancer Center, United States
7 publications · 2.3K citations
7
h-index
- JW
7
h-index
1–5 of 4.3K
Institutions
1.1K
Harvard University
Cambridge, United States
20 h-index
174 publications
40.9K citations
Dana-Farber Cancer Institute
Boston, United States
18 h-index
128 publications
27.8K citations
Broad Institute
Cambridge, United States
15 h-index
237 publications
40.7K citations
Brigham and Women's Hospital
Boston, United States
14 h-index
57 publications
10.5K citations
Wellcome Sanger Institute
Cambridge, United Kingdom
14 h-index
299 publications
79.2K citations
Memorial Sloan Kettering Cancer Center
New York, United States
14 h-index
135 publications
11.8K citations
The University of Texas MD Anderson Cancer Center
Houston, United States
13 h-index
137 publications
8.2K citations
Washington University in St. Louis
St Louis, United States
13 h-index
145 publications
21.6K citations
1–8 of 1.1K
Venues
- Bioinformatics
15 publications · 5.9K citations
15
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- Nature Communications
10 publications · 832 citations
10
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- bioRxiv (Cold Spring Harbor Laboratory)
Repository · 11 publications · 1K citations
10
h-index
- Nature Genetics
9 publications · 3.9K citations
9
h-index
- Scientific Reports
8 publications · 317 citations
8
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1–5