Concepedia

Solvent-accessible Surface Minimization

Solvent-Accessible Surface Minimization is an energy minimization method that reduces the solvent-accessible surface area of a molecular structure to stabilize its conformation by minimizing hydrophobic exposure in aqueous environments.

41

Publications

3.8K

Citations

162

Authors

77

Institutions

Publications per year

2017–2026

7

Parents

Publications

41

GEPOL: An improved description of molecular surfaces. III. A new algorithm for the computation of a solvent‐excluding surface

Juan-Luis Pascual-Ahuir, Estanislao Silla, Iñaki Tuñón · Journal of Computational Chemistry · 1994 · 925 citations

, , +15

Solvent accessible surface area and excluded volume in proteins

Timothy J. Richmond · Journal of Molecular Biology · 1984 · 742 citations

, , +12

POPS: a fast algorithm for solvent accessible surface areas at atomic and residue level

Luigi Cavallo · Nucleic Acids Research · 2003 · 228 citations · Full text

, , +17

Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5

Matteo Rossi Sebastiano, B.C. Doak, Maria Backlund et al. · Journal of Medicinal Chemistry · 2018 · 223 citations · Full text

, , +17

Solvent-accessible surfaces of nucleic acids

Charles J. Alden, Sung‐Hou Kim · Journal of Molecular Biology · 1979 · 165 citations

, , +14

1–5 of 41

Authors

162

  1. TC
    Tzu-Hsiu Cheng

    Yuan Ze University, Taiwan

    2 publications · 45 citations

    2

    h-index

  2. JW
    J�rg Weiser

    Columbia University, United States

    2 publications · 91 citations

    2

    h-index

  3. SC
    Shu-An Chen

    Yuan Ze University, Taiwan

    2 publications · 45 citations

    2

    h-index

  4. JC
    Jeremy C. Smith

    Oak Ridge National Laboratory, United States

    2 publications · 64 citations

    2

    h-index

  5. TL
    Tzong-Yi Lee

    Yuan Ze University, Taiwan

    2 publications · 45 citations

    2

    h-index

1–5 of 162

Institutions

77

  1. Columbia University

    New York, United States

    3 h-index

    10 publications

    424 citations

  2. Cornell University

    Ithaca, United States

    3 h-index

    13 publications

    1.5K citations

  3. Centro Científico Tecnológico - San Luis

    San Luis, Argentina

    2 h-index

    2 publications

    219 citations

  4. Uppsala University

    Uppsala, Sweden

    2 h-index

    6 publications

    1.1K citations

  5. National University of San Luis

    San Luis, Argentina

    2 h-index

    2 publications

    219 citations

  6. ETH Zurich

    Zurich, Switzerland

    2 h-index

    3 publications

    117 citations

  7. International Union of Biological Sciences

    Paris, France

    2 h-index

    2 publications

    219 citations

  8. Universitat Autònoma de Barcelona

    Cerdanyola del Vallès, Spain

    2 h-index

    6 publications

    180 citations

1–8 of 77

Venues

  1. Journal of Computational Chemistry

    7 publications · 1.3K citations

    7

    h-index

  2. The Journal of Physical Chemistry B

    4 publications · 118 citations

    4

    h-index

  3. Journal of Computer-Aided Molecular Design

    3 publications · 109 citations

    3

    h-index

  4. Journal of Molecular Biology

    JMB · 3 publications · 925 citations

    3

    h-index

  5. Journal of Medicinal Chemistry

    2 publications · 272 citations

    2

    h-index

1–5