Concepedia

Single-variant Association Analysis

Single-Variant Association Analysis is a statistical inference method used in rare variant association studies that evaluates the relationship between individual genetic variants and phenotypic traits by testing each variant separately for association, thereby distinguishing it from aggregated or gene-based analytic approaches.

164

Publications

8.9K

Citations

1.9K

Authors

715

Institutions

Publications per year

2017–2026

83

Variants

Single-variant Association Study

Parents

Publications

164

<i>SLCO1B1</i> Variants and Statin-Induced Myopathy — A Genomewide Study

New England Journal of Medicine · 2008 · 2K citations · Full text

, , +16

Rare variant contribution to human disease in 281,104 UK Biobank exomes

Quanli Wang, Ryan S. Dhindsa, Keren Carss et al. · Nature · 2021 · 604 citations · Full text

, , +17

Shifting Paradigm of Association Studies: Value of Rare Single-Nucleotide Polymorphisms

Ivan P. Gorlov, Olga Y. Gorlova, Shamil Sunyaev et al. · The American Journal of Human Genetics · 2008 · 339 citations · Full text

, , +14

Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes

Konrad J. Karczewski, Matthew Solomonson, Katherine R. Chao et al. · Cell Genomics · 2022 · 295 citations · Full text

, , +14

Firth logistic regression for rare variant association tests

Xuefeng Wang · Frontiers in Genetics · 2014 · 254 citations · Full text

, , +13

1–5 of 164

Authors

1.9K

  1. EB
    Eric Boerwinkle

    The University of Texas Health Science Center at Houston, United States

    7 publications · 231 citations

    7

    h-index

  2. MF
    Myriam Fornage

    The University of Texas Health Science Center at Houston, United States

    4 publications · 125 citations

    4

    h-index

  3. MM
    Markus M. Nöthen

    University of Bonn, Germany

    4 publications · 190 citations

    4

    h-index

  4. AF
    André Franke

    Christian-Albrechts-Universität zu Kiel, Germany

    4 publications · 106 citations

    4

    h-index

  5. SV
    Stephen V. Faraone

    SUNY Upstate Medical University, United States

    3 publications · 57 citations

    3

    h-index

1–5 of 1.9K

Institutions

715

  1. Broad Institute

    Cambridge, United States

    13 h-index

    59 publications

    9.5K citations

  2. National Institutes of Health

    Bethesda, United States

    12 h-index

    36 publications

    1.4K citations

  3. University of Washington

    Seattle, United States

    11 h-index

    29 publications

    977 citations

  4. The University of Texas Health Science Center at Houston

    Houston, United States

    11 h-index

    38 publications

    1K citations

  5. University of Oxford

    Oxford, United Kingdom

    11 h-index

    24 publications

    3.2K citations

  6. Karolinska Institutet

    Stockholm, Sweden

    11 h-index

    30 publications

    1.6K citations

  7. Harvard University

    Cambridge, United States

    10 h-index

    23 publications

    1.2K citations

  8. Inserm

    Paris, France

    10 h-index

    35 publications

    1.3K citations

1–8 of 715

Venues

  1. PLoS ONE

    10 publications · 270 citations

    10

    h-index

  2. Frontiers in Genetics

    7 publications · 409 citations

    7

    h-index

  3. Scientific Reports

    7 publications · 143 citations

    7

    h-index

  4. Genetic Epidemiology

    6 publications · 223 citations

    6

    h-index

  5. 6

    h-index

1–5