Concepedia

Single-strand Break Sensing

Single-Strand Break Sensing is a molecular detection mechanism within the DNA damage response pathway that specifically identifies and signals the presence of single-strand breaks in DNA to initiate repair.

21

Publications

1.6K

Citations

103

Authors

50

Institutions

Publications per year

2017–2026

6

Parents

Publications

21

Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1

Sebastian Eustermann, Wing-Fung Wu, Marie-France Langelier et al. · Molecular Cell · 2015 · 329 citations · Full text

, , +17

XRCC1 prevents toxic PARP1 trapping during DNA base excision repair

Annie Albert Demin, Kouji Hirota, Masataka Tsuda et al. · Molecular Cell · 2021 · 201 citations · Full text

, , +17

Detection and repair of single-strand breaks in nuclear DNA

Peter R. Cook, I. A. Brazell · Nature · 1976 · 189 citations

, , +14

Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair

Anna Campalans, Thierry Kortulewski, Rachel Amouroux et al. · Nucleic Acids Research · 2013 · 106 citations · Full text

, , +17

Detection and measurement of single-strand breaks in nuclear DNA in fixed lens sections

Sohan P. Modak, F.J. Bollum · Experimental Cell Research · 1972 · 97 citations

, , +9

1–5 of 21

Authors

103

  1. KW
    Keith W. Caldecott

    University of Sussex, United Kingdom

    4 publications · 368 citations

    4

    h-index

  2. HH
    Hana Hanzlíková

    Czech Academy of Sciences, Institute of Molecular Genetics, Czechia

    3 publications · 285 citations

    3

    h-index

  3. AA
    Annie Albert Demin

    University of Sussex, United Kingdom

    3 publications · 285 citations

    3

    h-index

  4. MA
    Marek Adamowicz

    University of Sussex, United Kingdom

    3 publications · 285 citations

    3

    h-index

  5. JB
    Jan Bražina

    Czech Academy of Sciences, Institute of Molecular Genetics, Czechia

    3 publications · 285 citations

    3

    h-index

1–5 of 103

Institutions

50

  1. University of Sussex

    Brighton, United Kingdom

    4 h-index

    33 publications

    3K citations

  2. CEA Paris-Saclay - Etablissement de Fontenay-aux-roses

    Fontenay-aux-Roses, France

    2 h-index

    10 publications

    840 citations

  3. Johannes Gutenberg University Mainz

    Mainz, Germany

    2 h-index

    5 publications

    138 citations

  4. Czech Academy of Sciences, Institute of Molecular Genetics

    Prague, Czechia

    2 h-index

    5 publications

    749 citations

  5. Kyoto University

    Kyoto, Japan

    2 h-index

    8 publications

    848 citations

  6. Commissariat à l'Énergie Atomique et aux Énergies Alternatives

    Paris, France

    2 h-index

    10 publications

    840 citations

  7. Institut de Radiobiologie Cellulaire et Moléculaire

    Fontenay-aux-Roses, France

    2 h-index

    9 publications

    789 citations

  8. University of Applied Sciences Mainz

    Mainz, Germany

    1 h-index

    2 publications

    102 citations

1–8 of 50

Venues

  1. Molecular Cell

    3 publications · 572 citations

    3

    h-index

  2. Nucleic Acids Research

    1 publications · 106 citations

    1

    h-index

  3. Electroanalysis

    1 publications · 35 citations

    1

    h-index

  4. 1

    h-index

  5. Journal of Molecular Biology

    JMB · 1 publications · 71 citations

    1

    h-index

1–5