Concepedia

Single-molecule Variant Detection

Single-Molecule Variant Detection is a genomic analysis method that identifies genetic variants by directly interrogating individual DNA molecules to enable high-resolution, haplotype-resolved, and low-frequency variant detection with reduced amplification bias.

40

Publications

6.8K

Citations

350

Authors

121

Institutions

Publications per year

2017–2026

19

Parents

Publications

40

Accurate detection of complex structural variations using single-molecule sequencing

Fritz J. Sedlazeck, Philipp Rescheneder, Moritz Smolka et al. · Nature Methods · 2018 · 1.9K citations

, , +15

Mutation detection and single-molecule counting using isothermal rolling-circle amplification

Paul M. Lizardi, Xiaohua Huang, Zhengrong Zhu et al. · Nature Genetics · 1998 · 1.4K citations

, , +14

Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations

Devin Dressman, Hai Yan, Giovanni Traverso et al. · Proceedings of the National Academy of Sciences · 2003 · 830 citations · Full text

, , +11

Single-Molecule Detection of Epidermal Growth Factor Receptor Mutations in Plasma by Microfluidics Digital PCR in Non–Small Cell Lung Cancer Patients

T. Yung, K.C. Chan, Tony Mok et al. · Clinical Cancer Research · 2009 · 383 citations

, , +17

Single molecule molecular inversion probes for targeted, high-accuracy detection of low-frequency variation

Joseph B. Hiatt, Colin C. Pritchard, Stephen J. Salipante et al. · Genome Research · 2013 · 348 citations · Full text

, , +16

1–5 of 40

Authors

350

  1. JV
    Joris Vermeesch

    KU Leuven, Belgium

    2 publications · 76 citations

    2

    h-index

  2. AH
    Alexander Hoischen

    Radboud University Nijmegen, Netherlands

    2 publications · 209 citations

    2

    h-index

  3. WZ
    Weiye Zhong

    Harvard University, United States

    2 publications · 24 citations

    2

    h-index

  4. MS
    Matthew S. Hestand

    KU Leuven, Belgium

    2 publications · 76 citations

    2

    h-index

  5. XS
    Xin Su

    Beijing University of Chemical Technology, China

    2 publications · 57 citations

    2

    h-index

1–5 of 350

Institutions

121

  1. Berry Oncology (China)

    Fuzhou, China

    3 h-index

    5 publications

    119 citations

  2. University of Washington

    Seattle, United States

    3 h-index

    8 publications

    1.6K citations

  3. Center for Human Genetics

    Bar Harbor, United States

    2 h-index

    9 publications

    370 citations

  4. New York Genome Center

    New York, United States

    2 h-index

    4 publications

    340 citations

  5. KU Leuven

    Leuven, Belgium

    2 h-index

    14 publications

    540 citations

  6. Radboud University Nijmegen

    Nijmegen, The Netherlands

    2 h-index

    32 publications

    2.9K citations

  7. Shenzhen University

    Shenzhen, China

    2 h-index

    14 publications

    164 citations

  8. Beijing University of Chemical Technology

    Beijing, China

    2 h-index

    11 publications

    288 citations

1–8 of 121

Venues

  1. Journal of Molecular Diagnostics

    JMD · 4 publications · 235 citations

    4

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 1.2K citations

    4

    h-index

  3. Genome Research

    GR · 3 publications · 480 citations

    3

    h-index

  4. Journal of the American Chemical Society

    JACS · 2 publications · 113 citations

    2

    h-index

  5. Nucleic Acids Research

    2 publications · 87 citations

    2

    h-index

1–5