Accurate detection of complex structural variations using single-molecule sequencing

Fritz J. Sedlazeck, Philipp Rescheneder, Moritz Smolka, +4

Nature Methods

Long-read SequencingNatural SciencesComputational BiologyMolecular BiologyComplex Structural Variations +5

Thiol-linked alkylation of RNA to assess expression dynamics

Veronika A. Herzog, Brian Reichholf, Tobias Neumann, +7

Nature Methods

Systems BiologyThiol-linked AlkylationEngineeringNatural SciencesRna Structure Prediction +3

NextGenMap: fast and accurate read mapping in highly polymorphic genomes

Fritz J. Sedlazeck, Philipp Rescheneder, Arndt von Haeseler

Bioinformatics

SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis

Matthias Muhar, Anja Ebert, Tobias Neumann, +17

Science

GeneticsMolecular BiologyGene Regulatory NetworkDirect TargetsRegulatory Pathways +14

Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line

Maria Nattestad, Sara Goodwin, Karen Ng, +16

Genome Research

A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha

Kevin Gesson, Philipp Rescheneder, Michael Skoruppa, +3

Genome Research

Molecular RegulationEpigenetic ChangeGeneticsMolecular BiologyA-type Lamins +15

Accurate detection of complex structural variations using single molecule sequencing

Fritz J. Sedlazeck, Philipp Rescheneder, Moritz Smolka, +4

EngineeringStructural BioinformaticsGeneticsMolecular BiologyGenomics +21

Quantification of experimentally induced nucleotide conversions in high-throughput sequencing datasets

Tobias Neumann, Veronika A. Herzog, Matthias Muhar, +4

BMC Bioinformatics

The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation

Dan Drecktrah, Meghan Lybecker, Niko Popitsch, +3

PLoS Pathogens

BiologyGlobal Gene ExpressionBiochemistryPpgpp LevelsMedicine +12

Revisiting the coding potential of the<i>E. coli</i>genome through Hfq co-immunoprecipitation

Ivana Bilusic, Niko Popitsch, Philipp Rescheneder, +2

RNA Biology