Concepedia

Single-cell Somatic Mutation Detection

Single-Cell Somatic Mutation Detection is a computational method designed to identify acquired genetic alterations in individual cells by distinguishing true somatic variants from technical artifacts inherent in single-cell sequencing data.

34

Publications

5.2K

Citations

322

Authors

157

Institutions

Publications per year

2017–2026

20

Parents

Publications

34

Aging and neurodegeneration are associated with increased mutations in single human neurons

Michael A. Lodato, Rachel E. Rodin, Craig L. Bohrson et al. · Science · 2017 · 655 citations · Full text

, , +17

Somatic mutation in single human neurons tracks developmental and transcriptional history

Michael A. Lodato, Mollie B. Woodworth, Semin Lee et al. · Science · 2015 · 588 citations

, , +17

Somatic mutation landscapes at single-molecule resolution

Federico Abascal, Luke M. R. Harvey, Emily Mitchell et al. · Nature · 2021 · 576 citations · Full text

, , +12

Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain

Gilad D. Evrony, Xuyu Cai, Eunjung Lee et al. · Cell · 2012 · 560 citations · Full text

, , +16

Single-cell mutation analysis of clonal evolution in myeloid malignancies

Linde A. Miles, Robert L. Bowman, Tiffany R. Merlinsky et al. · Nature · 2020 · 529 citations · Full text

, , +16

1–5 of 34

Authors

322

  1. CA
    Christopher A. Walsh

    Harvard University, United States

    8 publications · 2.3K citations

    8

    h-index

  2. PJ
    Peter J. Park

    Harvard University, United States

    8 publications · 2.2K citations

    8

    h-index

  3. MA
    Michael A. Lodato

    Harvard University, United States

    6 publications · 1.6K citations

    6

    h-index

  4. LJ
    Lovelace J. Luquette

    Harvard University, United States

    6 publications · 1.6K citations

    6

    h-index

  5. CL
    Craig L. Bohrson

    Harvard University, United States

    4 publications · 796 citations

    4

    h-index

1–5 of 322

Institutions

157

  1. Harvard University

    Cambridge, United States

    13 h-index

    98 publications

    28.5K citations

  2. Brigham and Women's Hospital

    Boston, United States

    11 h-index

    17 publications

    5.1K citations

  3. Broad Institute

    Cambridge, United States

    10 h-index

    49 publications

    13.5K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    28 publications

    9.8K citations

  5. Boston Children's Hospital

    Boston, United States

    7 h-index

    52 publications

    15.2K citations

  6. Albert Einstein College of Medicine

    Bronx, United States

    4 h-index

    35 publications

    3.2K citations

  7. Wellcome Sanger Institute

    Cambridge, United Kingdom

    4 h-index

    49 publications

    20.1K citations

  8. Shanghai Jiao Tong University

    Shanghai, China

    3 h-index

    3 publications

    254 citations

1–8 of 157

Venues

  1. Nature

    4 publications · 1.6K citations

    4

    h-index

  2. Science

    3 publications · 1.3K citations

    3

    h-index

  3. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 3 publications · 51 citations

    3

    h-index

  4. Genome biology

    2 publications · 62 citations

    2

    h-index

  5. Nature Genetics

    2 publications · 230 citations

    2

    h-index

1–5