Concepedia

Simultaneous Gene Targeting

Simultaneous Gene Targeting is a genome editing strategy that enables the coordinated modification of multiple genomic loci within a single experimental instance, distinguishing it from sequential or single-gene targeting approaches by its capacity for concurrent intervention.

69

Publications

4.3K

Citations

499

Authors

176

Institutions

Publications per year

2017–2026

32

Parents

Publications

69

CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome

Ha Youn Shin, Chaochen Wang, Hye‐Kyung Lee et al. · Nature Communications · 2017 · 344 citations · Full text

, , +13

Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin

Chengbin Wu, Ying Hua, Christine Grinnell et al. · Nature Biotechnology · 2007 · 341 citations

, , +16

Development of Light‐Activated CRISPR Using Guide RNAs with Photocleavable Protectors

Piyush Jain, Vyas Ramanan, Arnout Schepers et al. · Angewandte Chemie International Edition · 2016 · 196 citations · Full text

, , +14

Simultaneous targeting of pea glutathione reductase and of a bacterial fusion protein to chloroplasts and mitochondria in transgenic tobacco

Gary Creissen, Helen Reynolds, Yongbiao Xue et al. · The Plant Journal · 1995 · 194 citations

, , +13

Genome-Wide Assessment of Efficiency and Specificity in CRISPR/Cas9 Mediated Multiple Site Targeting in Arabidopsis

Brenda A. Peterson, David C. Haak, Marc T. Nishimura et al. · PLoS ONE · 2016 · 179 citations · Full text

, , +17

1–5 of 69

Authors

499

  1. SN
    Sangeeta N. Bhatia

    Massachusetts Institute of Technology, United States

    4 publications · 331 citations

    4

    h-index

  2. JP
    Joelle P. Straehla

    Massachusetts Institute of Technology, United States

    2 publications · 101 citations

    2

    h-index

  3. NS
    Nisha S. Dalvie

    Broad Institute, United States

    2 publications · 230 citations

    2

    h-index

  4. LH
    Lothar Hennighausen

    National Institute of Diabetes and Digestive and Kidney Diseases, United States

    2 publications · 364 citations

    2

    h-index

  5. TB
    Thomas B. Jacobs

    VIB-UGent Center for Plant Systems Biology, Belgium

    2 publications · 52 citations

    2

    h-index

1–5 of 499

Institutions

176

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    8 h-index

    16 publications

    1.1K citations

  2. Massachusetts Institute of Technology

    Cambridge, United States

    5 h-index

    43 publications

    3.2K citations

  3. Broad Institute

    Cambridge, United States

    5 h-index

    6 publications

    371 citations

  4. Brigham and Women's Hospital

    Boston, United States

    5 h-index

    6 publications

    419 citations

  5. Harvard University

    Cambridge, United States

    4 h-index

    8 publications

    317 citations

  6. Technical University of Munich

    Munich, Germany

    3 h-index

    6 publications

    427 citations

  7. Hanyang University

    Seoul, South Korea

    2 h-index

    11 publications

    432 citations

  8. National Institutes of Health

    Bethesda, United States

    2 h-index

    15 publications

    3.5K citations

1–8 of 176

Venues

  1. Biomaterials

    3 publications · 165 citations

    3

    h-index

  2. Nature Communications

    3 publications · 563 citations

    3

    h-index

  3. Blood

    2 publications · 206 citations

    2

    h-index

  4. Molecular and Cellular Biology

    MCB · 2 publications · 63 citations

    2

    h-index

  5. Molecular Therapy

    2 publications · 44 citations

    2

    h-index

1–5