Christine Grinnell

Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin

Chengbin Wu, Ying Hua, Christine Grinnell et al. · Nature Biotechnology · 2007 · 334 citations

Systems Biology, Engineering, Allergy +11

RGMa inhibition with human monoclonal antibodies promotes regeneration, plasticity and repair, and attenuates neuropathic pain after spinal cord injury

Andrea J. Mothe, Nardos G. Tassew, Alirezha P. Shabanzadeh et al. · Scientific Reports · 2017 · 87 citations · Full text

Pain Medicine, Immunology, Neuropathic Pain +20

Studies in serum support rapid formation of disulfide bond between unpaired cysteine residues in the VH domain of an immunoglobulin G1 molecule

David Ouellette, Leslie Alessandri, Adam T. Chin et al. · Analytical Biochemistry · 2009 · 68 citations

Protein Chemistry, Immunoglobulin G1 Molecule, Protein Function +11

Targeting Anti–TGF-β Therapy to Fibrotic Kidneys with a Dual Specificity Antibody Approach

Steve McGaraughty, Rachel Davis‐Taber, Chang Zhu et al. · Journal of the American Society of Nephrology · 2017 · 53 citations · Full text

Elezanumab, a human anti-RGMa monoclonal antibody, promotes neuroprotection, neuroplasticity, and neurorecovery following a thoracic hemicompression spinal cord injury in non-human primates

Peer B. Jacobson, Robin J Goody, Matthew S. Lawrence et al. · Neurobiology of Disease · 2021 · 41 citations · Full text