Christine Grinnell

Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin

Chengbin Wu, Ying Hua, Christine Grinnell et al. · Nature Biotechnology · 2007 · 341 citations

Life Sciences, Biotechnology, Immunology +16

RGMa inhibition with human monoclonal antibodies promotes regeneration, plasticity and repair, and attenuates neuropathic pain after spinal cord injury

Andrea J. Mothe, Nardos G. Tassew, Alirezha P. Shabanzadeh et al. · Scientific Reports · 2017 · 88 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Studies in serum support rapid formation of disulfide bond between unpaired cysteine residues in the VH domain of an immunoglobulin G1 molecule

David Ouellette, Leslie Alessandri, Adam T. Chin et al. · Analytical Biochemistry · 2009 · 71 citations

Life Sciences, Biochemistry, Molecular Biology +15

Targeting Anti–TGF-β Therapy to Fibrotic Kidneys with a Dual Specificity Antibody Approach

Steve McGaraughty, Rachel Davis‐Taber, Chang Zhu et al. · Journal of the American Society of Nephrology · 2017 · 53 citations

Medicine, Molecular Medicine, Nephrology +17

Elezanumab, a human anti-RGMa monoclonal antibody, promotes neuroprotection, neuroplasticity, and neurorecovery following a thoracic hemicompression spinal cord injury in non-human primates

Peer B. Jacobson, Robin J Goody, Matthew S. Lawrence et al. · Neurobiology of Disease · 2021 · 42 citations · Full text

Medicine, Neuroscience, Pharmacology +15