Concepedia

Shelterin Complex Function

Shelterin Complex Function is a molecular regulatory mechanism that belongs to the class of protein complex functions and specifically governs telomere protection and length maintenance by mediating the recruitment and activity of telomeric enzymes while preventing DNA damage responses at chromosome ends.

118

Publications

6.5K

Citations

850

Authors

323

Institutions

Publications per year

2017–2026

55

Parents

Publications

118

TINF2, a Component of the Shelterin Telomere Protection Complex, Is Mutated in Dyskeratosis Congenita

Sharon A. Savage, Neelam Giri, Gabriela M. Baerlocher et al. · The American Journal of Human Genetics · 2008 · 409 citations · Full text

, , +12

A Shared Docking Motif in TRF1 and TRF2 Used for Differential Recruitment of Telomeric Proteins

Yong Chen, Yuting Yang, Megan van Overbeek et al. · Science · 2008 · 270 citations

, , +17

A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly

Matthew S. O’Connor, Amin Safari, Huawei Xin et al. · Proceedings of the National Academy of Sciences · 2006 · 248 citations · Full text

, , +17

TIN2-Tethered TPP1 Recruits Human Telomerase to Telomeres <i>In Vivo</i>

Eladio Abreu, Elena Aritonovska, Patrick Reichenbach et al. · Molecular and Cellular Biology · 2010 · 236 citations · Full text

, , +14

Fission Yeast Pot1-Tpp1 Protects Telomeres and Regulates Telomere Length

Tomoichiro Miyoshi, Junko Kanoh, Motoki Saito et al. · Science · 2008 · 232 citations

, , +17

1–5 of 118

Authors

850

  1. TD
    Titia de Lange

    Rockefeller University, United States

    8 publications · 818 citations

    8

    h-index

  2. MA
    Marı́a A. Blasco

    Spanish National Cancer Research Centre, Spain

    5 publications · 290 citations

    5

    h-index

  3. GC
    Giovanni Cenci

    Sapienza University of Rome, Italy

    4 publications · 154 citations

    4

    h-index

  4. TM
    Taj Mohammad

    Jamia Millia Islamia, India

    4 publications · 127 citations

    4

    h-index

  5. GD
    Grazia D. Raffa

    Sapienza University of Rome, Italy

    4 publications · 154 citations

    4

    h-index

1–5 of 850

Institutions

323

  1. Rockefeller University

    New York, United States

    9 h-index

    29 publications

    3.2K citations

  2. Inserm

    Paris, France

    7 h-index

    40 publications

    2.3K citations

  3. National Institutes of Health

    Bethesda, United States

    6 h-index

    19 publications

    2.2K citations

  4. Spanish National Cancer Research Centre

    Madrid, Spain

    5 h-index

    32 publications

    2K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    34 publications

    2.3K citations

  6. National Cancer Institute

    Bethesda, United States

    5 h-index

    21 publications

    2.2K citations

  7. Jamia Millia Islamia

    New Delhi, India

    4 h-index

    21 publications

    705 citations

  8. Sapienza University of Rome

    Rome, Italy

    4 h-index

    34 publications

    1.3K citations

1–8 of 323

Venues

  1. Nucleic Acids Research

    10 publications · 554 citations

    10

    h-index

  2. Molecular and Cellular Biology

    MCB · 7 publications · 636 citations

    7

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 382 citations

    5

    h-index

  4. Genes & Development

    5 publications · 232 citations

    5

    h-index

  5. Nature Communications

    5 publications · 351 citations

    5

    h-index

1–5