Concepedia

Serine Catalysis

Serine Catalysis is a catalytic mechanism in enzymology wherein the hydroxyl group of a serine residue acts as a nucleophile to facilitate acid-base catalysis through covalent intermediate formation in the active site of certain hydrolases and transferases.

223

Publications

11.9K

Citations

813

Authors

272

Institutions

Publications per year

2017–2026

15

Parents

Publications

223

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

Michael E. Pacold, Kyle R. Brimacombe, Sze Ham Chan et al. · Nature Chemical Biology · 2016 · 589 citations · Full text

, , +14

The Enzymic Synthesis of l-Cysteine in Escherichia coli and Salmonella typhimurium

Nicholas M. Kredich, Gordon M. Tomkins · Journal of Biological Chemistry · 1966 · 439 citations · Full text

, , +14

Emil Knoevenagel and the Roots of Aminocatalysis

Benjamin List · Angewandte Chemie International Edition · 2010 · 285 citations

, , +14

Plasma Platelet-activating Factor Acetylhydrolase Is a Secreted Phospholipase A2 with a Catalytic Triad

Larry W. Tjoelker, Chris Eberhardt, Jeff Unger et al. · Journal of Biological Chemistry · 1995 · 216 citations · Full text

, , +16

The Three-Dimensional Structure of Asn <sup>102</sup> Mutant of Trypsin: Role of Asp <sup>102</sup> in Serine Protease Catalysis

Stephen R. Sprang, T. Standing, R.J. Fletterick et al. · Science · 1987 · 215 citations

, , +17

1–5 of 223

Authors

813

  1. VS
    Verne Schirch

    Virginia Commonwealth University, United States

    17 publications · 994 citations

    16

    h-index

  2. LS
    LaVerne Schirch

    Virginia Commonwealth University Medical Center, United States

    9 publications · 594 citations

    9

    h-index

  3. FB
    Francesco Bossa

    Sapienza University of Rome, Italy

    8 publications · 274 citations

    8

    h-index

  4. RC
    Roberto Contestabile

    Sapienza University of Rome, Italy

    7 publications · 298 citations

    7

    h-index

  5. SA
    Sebastiana Angelaccio

    Sapienza University of Rome, Italy

    6 publications · 333 citations

    6

    h-index

1–5 of 813

Institutions

272

  1. Virginia Commonwealth University

    Richmond, United States

    14 h-index

    48 publications

    2.3K citations

  2. University of Oxford

    Oxford, United Kingdom

    6 h-index

    21 publications

    1.1K citations

  3. Sapienza University of Rome

    Rome, Italy

    6 h-index

    36 publications

    2.1K citations

  4. Indian Institute of Science Bangalore

    Bengaluru, India

    6 h-index

    25 publications

    972 citations

  5. Bluffton University

    Bluffton, United States

    6 h-index

    12 publications

    772 citations

  6. Cornell University

    Ithaca, United States

    6 h-index

    16 publications

    958 citations

  7. Wesleyan University

    Middletown, United States

    5 h-index

    14 publications

    334 citations

  8. Scripps Research Institute

    San Diego, United States

    4 h-index

    13 publications

    865 citations

1–8 of 272

Venues

  1. Journal of Biological Chemistry

    JBC · 38 publications · 2.9K citations

    33

    h-index

  2. Biochemistry

    33 publications · 1.4K citations

    21

    h-index

  3. Journal of the American Chemical Society

    JACS · 11 publications · 636 citations

    11

    h-index

  4. European Journal of Biochemistry

    EJB · 8 publications · 267 citations

    8

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 7 publications · 197 citations

    7

    h-index

1–5