R.J. Fletterick

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

K M Pan, M. A. Baldwin, Jack Nguyen et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations · Full text

Prpsc Synthesis, Protein Chemistry, Protein Secretion +15

Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications.

J. Fernando Bazán, R.J. Fletterick · Proceedings of the National Academy of Sciences · 1988 · 424 citations · Full text

Protein Assembly, Virus Maturation, Molecular Biology +18

Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein.

T J Chambers, Ronald C. Weir, Arash Grakoui et al. · Proceedings of the National Academy of Sciences · 1990 · 350 citations · Full text

Virus Structure, Viral Replication, Sequence Homology +15

Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid.

Marı́a Gasset, M. A. Baldwin, D. H. Lloyd et al. · Proceedings of the National Academy of Sciences · 1992 · 328 citations · Full text

Alpha-helical Regions, Syrian Hamster Prp, Protein Function +13

The Three-Dimensional Structure of Asn ¹⁰² Mutant of Trypsin: Role of Asp ¹⁰² in Serine Protease Catalysis

Stephen R. Sprang, T. Standing, R.J. Fletterick et al. · Science · 1987 · 215 citations