Concepedia

Sequencing Depth Normalization

Sequencing Depth Normalization is a computational method used in microbial community profiling and single-cell quality control that adjusts sequencing data to account for variations in sequencing depth across samples, thereby enabling accurate comparison of microbial or cellular composition by scaling read counts to a common standard.

51

Publications

11K

Citations

263

Authors

119

Institutions

Publications per year

2017–2026

33

Variants

Read Count Normalization

Parents

Publications

51

Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression

Christoph Hafemeister · Genome biology · 2019 · 4.9K citations · Full text

, , +16

Differential expression in RNA-seq: A matter of depth

Sonia Tarazona, Fernando García-Alcalde, Joaquı́n Dopazo et al. · Genome Research · 2011 · 1.7K citations · Full text

, , +15

HiCRep: assessing the reproducibility of Hi-C data using a stratum-adjusted correlation coefficient

Tao Yang, Feipeng Zhang, Galip Gürkan Yardımcı et al. · Genome Research · 2017 · 617 citations · Full text

, , +15

Methods for normalizing microbiome data: An ecological perspective

Donald T. McKnight, Roger Huerlimann, Deborah S. Bower et al. · Methods in Ecology and Evolution · 2018 · 399 citations · Full text

, , +16

A field guide for the compositional analysis of any-omics data

Thomas P. Quinn, Ionas Erb, Gregory B. Gloor et al. · GigaScience · 2019 · 369 citations · Full text

, , +9

1–5 of 51

Authors

263

  1. QL
    Qunhua Li

    Pennsylvania State University, United States

    4 publications · 1K citations

    4

    h-index

  2. RC
    Ross C. Hardison

    Pennsylvania State University, United States

    3 publications · 738 citations

    3

    h-index

  3. GB
    Gregory B. Gloor

    Western University, Canada

    3 publications · 480 citations

    3

    h-index

  4. RK
    Rob Knight

    University of California San Diego, United States

    3 publications · 137 citations

    3

    h-index

  5. HZ
    Hongyu Zhao

    Yale University, United States

    2 publications · 59 citations

    2

    h-index

1–5 of 263

Institutions

119

  1. Pennsylvania State University

    State College, United States

    5 h-index

    21 publications

    4.8K citations

  2. University of New England

    Armidale, Australia

    3 h-index

    3 publications

    795 citations

  3. University of California San Diego

    San Diego, United States

    3 h-index

    23 publications

    907 citations

  4. Western University

    London, Canada

    3 h-index

    5 publications

    648 citations

  5. University of Pennsylvania

    Philadelphia, United States

    2 h-index

    2 publications

    120 citations

  6. New York Genome Center

    New York, United States

    2 h-index

    4 publications

    10.3K citations

  7. Oregon State University

    Corvallis, United States

    2 h-index

    2 publications

    120 citations

  8. Deakin University

    Burwood, Australia

    2 h-index

    4 publications

    792 citations

1–8 of 119

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 8 publications · 445 citations

    8

    h-index

  2. Nucleic Acids Research

    4 publications · 299 citations

    4

    h-index

  3. Genome biology

    4 publications · 5.2K citations

    4

    h-index

  4. BMC Bioinformatics

    3 publications · 166 citations

    3

    h-index

  5. BMC Genomics

    3 publications · 148 citations

    3

    h-index

1–5