Sequence-Specific DNA Cleavage is a biochemical process in which double- or single-stranded DNA is catalytically severed at precisely defined nucleotide sequences through the action of enzymes or synthetic agents engineered to recognize and bind those unique sequences.
475
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481
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2017–2026
54
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Publications
475
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text
A new method for predicting signal sequence cleavage sites
Gunnar von Heijne · Nucleic Acids Research · 1986 · 4.6K citations · Full text
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481
Centre National de la Recherche Scientifique
Paris, France
13 h-index
74 publications
3.1K citations
University of California, Los Angeles
Los Angeles, United States
11 h-index
37 publications
1.3K citations
Kyoto University
Kyoto, Japan
11 h-index
34 publications
2.5K citations
Inserm
Paris, France
11 h-index
57 publications
1.6K citations
Massachusetts Institute of Technology
Cambridge, United States
10 h-index
36 publications
1.5K citations
National Institutes of Health
Bethesda, United States
10 h-index
25 publications
1K citations
University of Virginia
Charlottesville, United States
10 h-index
40 publications
1.6K citations
New England Biolabs (United States)
Ipswich, United States
10 h-index
41 publications
3.8K citations
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- Nucleic Acids Research
88 publications · 9.4K citations
37
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- Proceedings of the National Academy of Sciences
PNAS · 34 publications · 11.4K citations
28
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- Journal of Biological Chemistry
JBC · 41 publications · 2.7K citations
27
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- Journal of the American Chemical Society
JACS · 32 publications · 2K citations
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- Biochemistry
32 publications · 1.4K citations
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