Concepedia

Sequence Kernel Association Tests

Sequence Kernel Association Test is a statistical method in rare variant association studies that aggregates the effects of multiple rare genetic variants within a genomic region using a kernel function to test for association with a phenotype while accounting for both risk and protective variants.

117

Publications

8K

Citations

1.3K

Authors

488

Institutions

Publications per year

2017–2026

52

Variants

Skat

Parents

Publications

117

Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test

Michael C. Wu, Seunggeun Lee, Tianxi Cai et al. · The American Journal of Human Genetics · 2011 · 2.5K citations · Full text

, , +14

Optimal tests for rare variant effects in sequencing association studies

S. Lee, Michael C. Wu, Xinyi Lin · Biostatistics · 2012 · 745 citations · Full text

, , +15

Sequence Kernel Association Tests for the Combined Effect of Rare and Common Variants

Iuliana Ionita‐Laza, Seunggeun Lee, Vlad Makarov et al. · The American Journal of Human Genetics · 2013 · 463 citations · Full text

, , +16

Excessive burden of lysosomal storage disorder gene variants in Parkinson’s disease

Laurie Robak, Iris E. Jansen, Jeroen van Rooij et al. · Brain · 2017 · 451 citations · Full text

, , +17

Sequence Kernel Association Test for Quantitative Traits in Family Samples

Han Chen, James B. Meigs, Josée Dupuis · Genetic Epidemiology · 2012 · 223 citations

, , +16

1–5 of 117

Authors

1.3K

  1. MC
    Michael C. Wu

    Fred Hutch Cancer Center, United States

    8 publications · 3.6K citations

    8

    h-index

  2. SL
    Seunggeun Lee

    University of Michigan, United States

    7 publications · 3.3K citations

    7

    h-index

  3. RF
    Ruzong Fan

    Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States

    6 publications · 215 citations

    6

    h-index

  4. MX
    Momiao Xiong

    The University of Texas Health Science Center at Houston, United States

    6 publications · 215 citations

    6

    h-index

  5. YW
    Yifan Wang

    The University of Texas Health Science Center at Houston, United States

    5 publications · 205 citations

    5

    h-index

1–5 of 1.3K

Institutions

488

  1. Harvard University

    Cambridge, United States

    14 h-index

    39 publications

    11.8K citations

  2. University of Washington

    Seattle, United States

    13 h-index

    44 publications

    1.2K citations

  3. The University of Texas Health Science Center at Houston

    Houston, United States

    13 h-index

    25 publications

    642 citations

  4. University of Michigan

    Ann Arbor, United States

    13 h-index

    26 publications

    3.2K citations

  5. Fred Hutch Cancer Center

    Seattle, United States

    10 h-index

    21 publications

    552 citations

  6. National Institutes of Health

    Bethesda, United States

    10 h-index

    43 publications

    1.4K citations

  7. University of Minnesota

    Minneapolis, United States

    9 h-index

    23 publications

    641 citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    9 h-index

    16 publications

    6.2K citations

1–8 of 488

Venues

  1. Genetic Epidemiology

    25 publications · 1.2K citations

    16

    h-index

  2. PLoS ONE

    6 publications · 132 citations

    6

    h-index

  3. The American Journal of Human Genetics

    AJHG · 5 publications · 3.1K citations

    5

    h-index

  4. Annals of Human Genetics

    4 publications · 94 citations

    4

    h-index

  5. BMC Medical Genomics

    4 publications · 111 citations

    4

    h-index

1–5