Concepedia

Self-immolative Decomposition

Self-Immolative Decomposition is a chemical process in which a molecular scaffold spontaneously undergoes a cascade of bond cleavages following an initial triggering event, distinguished by the autonomous and irreversible release of functional payloads without external intervention.

17

Publications

818

Citations

68

Authors

25

Institutions

Publications per year

2017–2026

8

Variants

Self-immolative Degradation

Parents

Publications

17

Single UV or Near IR Triggering Event Leads to Polymer Degradation into Small Molecules

Caroline de Gracia Lux, Cathryn L. McFearin, Shivanjali Joshi-Barr et al. · ACS Macro Letters · 2012 · 125 citations

, , +17

Inhibition of Mitochondrial Bioenergetics by Esterase-Triggered COS/H<sub>2</sub>S Donors

Andrea K. Steiger, Michela Marcatti, Csaba Szabó et al. · ACS Chemical Biology · 2017 · 86 citations · Full text

, , +17

The azaquinone-methide elimination: comparison study of 1,6- and 1,4-eliminations under physiological conditions

Rotem Erez, Doron Shabat · Organic & Biomolecular Chemistry · 2008 · 78 citations · Full text

, , +14

Kinetics of Self-Immolative Degradation in a Linear Polymeric System: Demonstrating the Effect of Chain Length

Ryan A. McBride, Elizabeth R. Gillies · Macromolecules · 2013 · 70 citations

, , +17

Facile Synthesis of H<sub>2</sub>O<sub>2</sub>-Cleavable Poly(ester-amide)s by Passerini Multicomponent Polymerization

Yang Cui, Mei Zhang, Fu‐Sheng Du et al. · ACS Macro Letters · 2016 · 69 citations

, , +15

1–5 of 17

Authors

68

  1. DS
    Doron Shabat

    Tel Aviv University, Israel

    3 publications · 163 citations

    3

    h-index

  2. RJ
    Roey J. Amir

    Tel Aviv University, Israel

    2 publications · 85 citations

    2

    h-index

  3. MD
    Michael D. Pluth

    University of Oregon, United States

    2 publications · 135 citations

    2

    h-index

  4. ER
    Elizabeth R. Gillies

    Western University, Canada

    2 publications · 118 citations

    2

    h-index

  5. FD
    Fu‐Sheng Du

    Peking University, China

    1 publications · 69 citations

    1

    h-index

1–5 of 68

Institutions

25

  1. Tel Aviv University

    Tel Aviv, Israel

    3 h-index

    8 publications

    411 citations

  2. Exact Sciences (United States)

    Madison, United States

    2 h-index

    2 publications

    134 citations

  3. Western University

    London, Canada

    2 h-index

    7 publications

    380 citations

  4. University of Oregon

    Eugene, United States

    2 h-index

    6 publications

    368 citations

  5. University College London

    London, United Kingdom

    1 h-index

    3 publications

    51 citations

  6. Université de Rouen Normandie

    Rouen, France

    1 h-index

    6 publications

    336 citations

  7. Beijing National Laboratory for Molecular Sciences

    Beijing, China

    1 h-index

    4 publications

    276 citations

  8. Material (Belgium)

    Brussels, Belgium

    1 h-index

    2 publications

    44 citations

1–8 of 25

Venues

  1. ACS Macro Letters

    2 publications · 194 citations

    2

    h-index

  2. Burns

    2 publications · 59 citations

    2

    h-index

  3. Organic & Biomolecular Chemistry

    2 publications · 93 citations

    2

    h-index

  4. Journal of Agricultural and Food Chemistry

    1 publications · 48 citations

    1

    h-index

  5. Suicide and Life-Threatening Behavior

    1 publications · 26 citations

    1

    h-index

1–5