Concepedia

Selenoprotein Dysfunction

Selenoprotein Dysfunction is a pathological condition characterized by the impaired synthesis or activity of selenoproteins, which are a class of proteins incorporating selenocysteine as a functional component, leading to disrupted redox homeostasis and cellular dysfunction due to selenium imbalance.

160

Publications

10.3K

Citations

1K

Authors

351

Institutions

Publications per year

2017–2026

47

Parents

Publications

160

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

Ishraq Alim, Joseph T. Caulfield, Yingxin Chen et al. · Cell · 2019 · 980 citations · Full text

, , +16

A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance

Hirofumi Misu, Toshinari Takamura, Hiroaki Takayama et al. · Cell Metabolism · 2010 · 570 citations · Full text

, , +16

Selenium Deficiency Is Associated with Mortality Risk from COVID-19

Arash Moghaddam, Raban Heller, Qian Sun et al. · Nutrients · 2020 · 362 citations · Full text

, , +15

Mutations in the selenocysteine insertion sequence–binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

Erik Schoenmakers, Maura Agostini, Catherine Mitchell et al. · Journal of Clinical Investigation · 2010 · 310 citations · Full text

, , +17

Keshan Disease, Selenium Deficiency, and the Selenoproteome

Joseph Loscalzo · New England Journal of Medicine · 2014 · 241 citations

, , +15

1–5 of 160

Authors

1K

  1. DL
    Dolph L. Hatfield

    National Institutes of Health, United States

    15 publications · 1K citations

    15

    h-index

  2. BA
    Bradley A. Carlson

    National Cancer Institute, United States

    15 publications · 1K citations

    15

    h-index

  3. VN
    Vadim N. Gladyshev

    Brigham and Women's Hospital, United States

    10 publications · 543 citations

    10

    h-index

  4. LS
    Lutz Schomburg

    Charité - Universitätsmedizin Berlin, Germany

    9 publications · 954 citations

    9

    h-index

  5. US
    Ulrich Schweizer

    Charité - Universitätsmedizin Berlin, Germany

    6 publications · 297 citations

    6

    h-index

1–5 of 1K

Institutions

351

  1. National Cancer Institute

    Bethesda, United States

    15 h-index

    49 publications

    3.6K citations

  2. National Institutes of Health

    Bethesda, United States

    13 h-index

    42 publications

    2.6K citations

  3. Charité - Universitätsmedizin Berlin

    Berlin, Germany

    11 h-index

    40 publications

    4.7K citations

  4. Brigham and Women's Hospital

    Boston, United States

    10 h-index

    19 publications

    1K citations

  5. Harvard University

    Cambridge, United States

    9 h-index

    19 publications

    1K citations

  6. Center for Cancer Research

    Bethesda, United States

    9 h-index

    22 publications

    1.6K citations

  7. Inserm

    Paris, France

    7 h-index

    26 publications

    2.4K citations

  8. University College London

    London, United Kingdom

    6 h-index

    13 publications

    1.6K citations

1–8 of 351

Venues

  1. Biological Trace Element Research

    16 publications · 588 citations

    14

    h-index

  2. Journal of Nutrition

    JN · 8 publications · 757 citations

    8

    h-index

  3. 5

    h-index

  4. PubMed

    Repository · 5 publications · 151 citations

    5

    h-index

  5. Journal of Biological Chemistry

    JBC · 4 publications · 289 citations

    4

    h-index

1–5