Concepedia

Selection Stringency

Selection Stringency is a methodological parameter in phage display that determines the rigor of selective pressure applied during iterative selection cycles to enrich high-affinity binders by differentiating target-specific interactions from nonspecific or low-affinity bindings.

35

Publications

2.2K

Citations

176

Authors

67

Institutions

Publications per year

2017–2026

12

Parents

Publications

35

Protein tolerance to random amino acid change

H. Henry Guo, Juno Choe, Lawrence A. Loeb · Proceedings of the National Academy of Sciences · 2004 · 327 citations · Full text

, , +13

D-peptide inhibitors of the p53–MDM2 interaction for targeted molecular therapy of malignant neoplasms

Min Liu, Chong Li, Marzena Pazgier et al. · Proceedings of the National Academy of Sciences · 2010 · 227 citations

, , +16

Negative selection and stringency modulation in phage-assisted continuous evolution

Jacob C. Carlson, Ahmed H. Badran, Drago A Guggiana-Nilo et al. · Nature Chemical Biology · 2014 · 175 citations · Full text

, , +12

CombiROC: an interactive web tool for selecting accurate marker combinations of omics data

Saveria Mazzara, Riccardo L. Rossi, Renata Grifantini et al. · Scientific Reports · 2017 · 141 citations · Full text

, , +17

High-Affinity Nucleic-Acid-Based Receptors for Steroids

Kyung-Ae Yang, Hyo-Sun Chun, Yameng Zhang et al. · ACS Chemical Biology · 2017 · 126 citations · Full text

, , +17

1–5 of 35

Authors

176

  1. AP
    Arie P. Otte

    University of Amsterdam, Netherlands

    4 publications · 74 citations

    4

    h-index

  2. JV
    John Verhees

    University of Amsterdam, Netherlands

    4 publications · 74 citations

    4

    h-index

  3. TS
    Tjalling Siersma

    University of Amsterdam, Netherlands

    2 publications · 31 citations

    2

    h-index

  4. NT
    N.C. Teunissen

    University of Amsterdam, Netherlands

    2 publications · 45 citations

    2

    h-index

  5. VN
    Vincent N. A. Klaren

    Combined Ophthalmic Research Rotterdam, Netherlands

    2 publications · 45 citations

    2

    h-index

1–5 of 176

Institutions

67

  1. Harvard University

    Cambridge, United States

    4 h-index

    13 publications

    1.2K citations

  2. University of Amsterdam

    Amsterdam, The Netherlands

    3 h-index

    17 publications

    292 citations

  3. University of California, Santa Barbara

    Santa Barbara, United States

    2 h-index

    3 publications

    165 citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    8 publications

    590 citations

  5. Korea Advanced Institute of Science and Technology

    Daejeon, South Korea

    2 h-index

    6 publications

    297 citations

  6. Weizmann Institute of Science

    Rehovot, Israel

    2 h-index

    2 publications

    116 citations

  7. Inserm

    Paris, France

    2 h-index

    5 publications

    62 citations

  8. Istituto Nazionale Genetica Molecolare

    Milan, Italy

    1 h-index

    6 publications

    846 citations

1–8 of 67

Venues

  1. Biotechnology Progress

    3 publications · 69 citations

    3

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 633 citations

    3

    h-index

  3. Biotechnology Journal

    2 publications · 45 citations

    2

    h-index

  4. Scientific Reports

    2 publications · 228 citations

    2

    h-index

  5. The Journal of Immunology

    JI · 1 publications · 10 citations

    1

    h-index

1–5