Concepedia

Sample-level Pathway Activity Estimation

Sample-Level Pathway Activity Estimation is a computational method that quantifies the functional state of biological pathways in individual samples by integrating molecular profiling data with prior knowledge of gene pathway membership, distinguishing it from population-level or aggregate approaches through its focus on per-sample activity inference.

5

Publications

16.7K

Citations

27

Authors

13

Institutions

Publications per year

2017–2026

3

Parents

Publications

5

GSVA: gene set variation analysis for microarray and RNA-Seq data

Sonja Hänzelmann, Robert Castelo, Justin Guinney · BMC Bioinformatics · 2013 · 16.5K citations · Full text

, , +17

Accurate and Reliable Cancer Classification Based on Probabilistic Inference of Pathway Activity

Junjie Su, Byung-Jun Yoon, Edward R. Dougherty · PLoS ONE · 2009 · 127 citations · Full text

, , +12

Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types

Anja van de Stolpe, Laurent Holtzer, Henk van Ooijen et al. · Scientific Reports · 2019 · 67 citations · Full text

, , +15

Survival analysis of pathway activity as a prognostic determinant in breast cancer

Gustavo S. Jeuken, Nicholas P. Tobin, Lukas Käll · PLoS Computational Biology · 2022 · 21 citations · Full text

, , +16

PerPAS: Topology-Based Single Sample Pathway Analysis Method

Chengyu Liu, Rainer Lehtonen, Sampsa Hautaniemi · IEEE/ACM Transactions on Computational Biology and Bioinformatics · 2017 · 13 citations · Full text

, , +17

1–5 of 5

Authors

27

  1. SY
    Shi Yao

    Xi'an Jiaotong University, China

    1 publications · 12 citations

    1

    h-index

  2. CW
    Chen Wang

    Mayo Clinic in Florida, United States

    1 publications · 12 citations

    1

    h-index

  3. YC
    Yi-Xiao Chen

    Second Affiliated Hospital of Xi'an Jiaotong University, China

    1 publications · 12 citations

    1

    h-index

  4. RC
    Robert Castelo

    Universitat Pompeu Fabra, Spain

    1 publications · 16.5K citations

    1

    h-index

  5. WV
    Wim Verhaegh

    Philips (Netherlands), Netherlands

    1 publications · 67 citations

    1

    h-index

1–5 of 27

Institutions

13

  1. Sage Bionetworks

    Seattle, United States

    1 h-index

    1 publications

    16.5K citations

  2. Texas A&M University

    College Station, United States

    1 h-index

    3 publications

    381 citations

  3. Xi'an Jiaotong University

    Xi'an, China

    1 h-index

    10 publications

    120 citations

  4. NXP (Netherlands)

    Eindhoven, The Netherlands

    1 h-index

    1 publications

    67 citations

  5. Translational Genomics Research Institute

    Phoenix, United States

    1 h-index

    1 publications

    127 citations

  6. Zhejiang University

    Hangzhou, China

    1 h-index

    1 publications

    12 citations

  7. University of Helsinki

    Helsinki, Finland

    1 h-index

    3 publications

    39 citations

  8. Second Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, China

    1 h-index

    4 publications

    48 citations

1–8 of 13

Venues

  1. Scientific Reports

    1 publications · 67 citations

    1

    h-index

  2. BMC Bioinformatics

    1 publications · 16.5K citations

    1

    h-index

  3. 1

    h-index

  4. PLoS ONE

    1 publications · 127 citations

    1

    h-index

  5. EBioMedicine

    1 publications · 12 citations

    1

    h-index

1–5