Henk van Ooijen

Selection of Personalized Patient Therapy through the Use of Knowledge-Based Computational Models That Identify Tumor-Driving Signal Transduction Pathways

Wim Verhaegh, Henk van Ooijen, Márcia A. Inda et al. · Cancer Research · 2014 · 91 citations

Signal Transduction Pathways, Engineering, Breast Oncology +22

Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types

Anja van de Stolpe, Laurent Holtzer, Henk van Ooijen et al. · Scientific Reports · 2019 · 59 citations · Full text

Assessment of Functional Phosphatidylinositol 3-Kinase Pathway Activity in Cancer Tissue Using Forkhead Box-O Target Gene Expression in a Knowledge-Based Computational Model

Henk van Ooijen, Marten Hornsveld, Christa Dam-de Veen et al. · American Journal Of Pathology · 2018 · 55 citations · Full text

A Molecular Test for Quantifying Functional Notch Signaling Pathway Activity in Human Cancer

Kirsten Canté-Barrett, Laurent Holtzer, Henk van Ooijen et al. · Cancers · 2020 · 27 citations · Full text

ER and PI3K Pathway Activity in Primary ER Positive Breast Cancer Is Associated with Progression-Free Survival of Metastatic Patients under First-Line Tamoxifen

Anieta M. Sieuwerts, Márcia A. Inda, Marcel Smid et al. · Cancers · 2020 · 25 citations · Full text