Concepedia

Route Of Administration Optimization

Route of Administration Optimization is a strategic framework in antibody formulation that systematically identifies and refines the most effective physiological pathway for delivering therapeutic antibodies to maximize bioavailability, minimize immunogenicity, and enhance target tissue engagement.

10

Publications

249

Citations

71

Authors

18

Institutions

Publications per year

2017–2026

3

Parents

Publications

10

Effect of cell culture medium components on color of formulated monoclonal antibody drug substance

Natarajan Vijayasankaran, Sharat Varma, Yi Yang et al. · Biotechnology Progress · 2013 · 61 citations

, , +17

Intrapericardial Administration of Mesenchymal Stem Cells in a Large Animal Model: A Bio-Distribution Analysis

Rebeca Blázquez, Francisco M. Sánchez‐Margallo, Verónica Crisóstomo et al. · PLoS ONE · 2015 · 39 citations · Full text

, , +12

Comparison of the lateral tail vein and the retro-orbital venous sinus routes of antibody administration in pharmacokinetic studies

Angela Schoch, Irmgard S. Thorey, Julia Engert et al. · Lab Animal · 2014 · 36 citations

, , +8

Optimization of monoclonal antibody delivery via the lymphatics: the dose dependence.

Michael A. Steller, Robert Parker, David G. Covell et al. · PubMed · 1986 · 30 citations

, , +16

Subcutaneous Site-of-Absorption Study with the Monoclonal Antibody Tocilizumab in Minipigs: Administration Behind Ear Translates Best to Humans

W. Richter, Hans-Peter Grimm, Marie-Hélène Gouy et al. · The AAPS Journal · 2020 · 21 citations

, , +11

1–5 of 10

Authors

71

  1. GP
    Giovanni Passalacqua

    University of Genoa, Italy

    1 publications · 16 citations

    1

    h-index

  2. NV
    Natarajan Vijayasankaran

    Oceanside Public Library, United States

    1 publications · 61 citations

    1

    h-index

  3. YZ
    Yishan Zheng

    University of Brighton, United Kingdom

    1 publications · 10 citations

    1

    h-index

  4. MA
    Michael A. Steller

    National Cancer Institute, United States

    1 publications · 30 citations

    1

    h-index

  5. SS
    Susi Søgaard

    Roche (Switzerland), Switzerland

    1 publications · 21 citations

    1

    h-index

1–5 of 71

Institutions

18

  1. Roche Pharma AG (Germany)

    Grenzach-Wyhlen, Germany

    2 h-index

    2 publications

    57 citations

  2. Institute for Regenerative Medicine & Biotherapy

    Montpellier, France

    1 h-index

    6 publications

    84 citations

  3. Institute for Liver Health

    Chandler, United States

    1 h-index

    2 publications

    20 citations

  4. University of Genoa

    Genoa, Italy

    1 h-index

    1 publications

    16 citations

  5. University College London

    London, United Kingdom

    1 h-index

    2 publications

    20 citations

  6. University of Brighton

    Brighton, United Kingdom

    1 h-index

    4 publications

    40 citations

  7. Centro de Cirugía de Mínima Invasión Jesús Usón

    Cáceres, Spain

    1 h-index

    9 publications

    351 citations

  8. National Institutes of Health

    Bethesda, United States

    1 h-index

    5 publications

    150 citations

1–8 of 18

Venues

  1. Journal of Controlled Release

    2 publications · 26 citations

    2

    h-index

  2. PubMed

    Repository · 2 publications · 46 citations

    2

    h-index

  3. Lab Animal

    1 publications · 36 citations

    1

    h-index

  4. Archives of Dermatology and Syphilology

    1 publications · 10 citations

    1

    h-index

  5. Scientific Reports

    1 publications · 10 citations

    1

    h-index

1–5