Concepedia

Subcutaneous Site-of-Absorption Study with the Monoclonal Antibody Tocilizumab in Minipigs: Administration Behind Ear Translates Best to Humans

W. Richter, Hans-Peter Grimm, Marie-Hélène Gouy, Susi Søgaard, Caroline Kreuzer, Uwe Wessels, Dragomir Draganov, Chris Muenzer, Tonio Hoche

The AAPS Journal · 2020 · 21 citations · 19 references

DOI

Concepts

References

19

Effect of Molecular Weight on the Lymphatic Absorption of Water-Soluble Compounds Following Subcutaneous Administration

A. Supersaxo, W. Hein, Hans‐Michael Steffen · Pharmaceutical Research · 1990 · 383 citations

, , +17

Subcutaneous Absorption of Biotherapeutics: Knowns and Unknowns

W. Richter, Björn Jacobsen · Drug Metabolism and Disposition · 2014 · 222 citations

, , +17

Alterations in Insulin Absorption and in Blood Glucose Control Associated with Varying Insulin Injection Sites in Diabetic Patients

V A Koivisto, Philip Felig · Annals of Internal Medicine · 1980 · 155 citations

, , +15

Quantitative Prediction of Human Pharmacokinetics for Monoclonal Antibodies

Jennifer Dong, David H. Salinger, Christopher J. Endres et al. · Clinical Pharmacokinetics · 2011 · 154 citations

, , +16

Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration

Yanan Zheng, Devin B. Tesar, Lisa J. Benincosa et al. · mAbs · 2012 · 144 citations · Full text

, , +17