Concepedia

Risc Assembly

RISC Assembly is a molecular mechanism in the RNA interference pathway that refers to the process by which the RNA-induced silencing complex (RISC) is formed through the loading of a small noncoding RNA, typically a small interfering RNA (siRNA) or microRNA (miRNA), onto an Argonaute protein, thereby enabling sequence-specific post-transcriptional gene silencing.

92

Publications

15.2K

Citations

477

Authors

181

Institutions

Publications per year

2017–2026

17

Parents

Publications

92

MicroRNA: Biogenesis, Function and Role in Cancer

Leigh-Ann MacFarlane, Paul R. Murphy · Current Genomics · 2010 · 1.8K citations · Full text

, , +16

Human RISC Couples MicroRNA Biogenesis and Posttranscriptional Gene Silencing

Richard I. Gregory, Thimmaiah P. Chendrimada, Neil Cooch et al. · Cell · 2005 · 1.6K citations · Full text

, , +14

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

Katsutomo Okamura, Akira Ishizuka, Haruhiko Siomi et al. · Genes & Development · 2004 · 842 citations · Full text

, , +17

Purified Argonaute2 and an siRNA form recombinant human RISC

Fabiola V. Rivas, Niraj H. Tolia, Ji‐Joon Song et al. · Nature Structural & Molecular Biology · 2005 · 775 citations

, , +10

A Protein Sensor for siRNA Asymmetry

Yukihide Tomari, Christian B. Matranga, Benjamin Haley et al. · Science · 2004 · 594 citations

, , +17

1–5 of 92

Authors

477

  1. YT
    Yukihide Tomari

    The University of Tokyo, Japan

    10 publications · 1.9K citations

    10

    h-index

  2. RI
    Richard I. Gregory

    Harvard University, United States

    4 publications · 1.8K citations

    4

    h-index

  3. JM
    Javier Martı̂nez

    Institute of Molecular Biotechnology, Austria

    3 publications · 1K citations

    3

    h-index

  4. GM
    Gunter Meister

    University of Regensburg, Germany

    3 publications · 367 citations

    3

    h-index

  5. TK
    Tomoko Kawamata

    The University of Tokyo, Japan

    3 publications · 361 citations

    3

    h-index

1–5 of 477

Institutions

181

  1. The University of Tokyo

    Tokyo, Japan

    10 h-index

    26 publications

    2.1K citations

  2. Harvard University

    Cambridge, United States

    6 h-index

    21 publications

    4.4K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    31 publications

    3.8K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    9 publications

    2.4K citations

  5. University of Pennsylvania

    Philadelphia, United States

    4 h-index

    16 publications

    2K citations

  6. The University of Texas Southwestern Medical Center

    Dallas, United States

    4 h-index

    25 publications

    3.2K citations

  7. Northwestern University

    Evanston, United States

    3 h-index

    6 publications

    402 citations

  8. University of Massachusetts Chan Medical School

    Worcester, United States

    3 h-index

    16 publications

    6.8K citations

1–8 of 181

Venues

  1. RNA

    9 publications · 799 citations

    9

    h-index

  2. Nucleic Acids Research

    8 publications · 647 citations

    8

    h-index

  3. Cell

    6 publications · 3.4K citations

    6

    h-index

  4. Nature Structural & Molecular Biology

    6 publications · 2.1K citations

    6

    h-index

  5. Molecular Cell

    4 publications · 325 citations

    4

    h-index

1–5