Concepedia

Ret Mutations

RET Mutations is a genetic alteration in the RET proto-oncogene, characterized by specific gain-of-function mutations or rearrangements that lead to constitutive activation of the RET receptor tyrosine kinase, thereby driving oncogenic signaling in various cancers.

1.1K

Publications

79.3K

Citations

5.8K

Authors

1.5K

Institutions

Publications per year

2017–2026

190

Parents

Publications

1.1K

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A

Lois M. Mulligan, John B. Kwok, Catherine S. Healey et al. · Nature · 1993 · 2K citations

, , +16

RET, ROS1 and ALK fusions in lung cancer

Kengo Takeuchi, Manabu Soda, Yuki Togashi et al. · Nature Medicine · 2012 · 1.3K citations

, , +14

Cabozantinib in Progressive Medullary Thyroid Cancer

Rossella Elisei, Martin Schlumberger, Stefan Müller et al. · Journal of Clinical Oncology · 2013 · 1.2K citations · Full text

, , +14

A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma

Robert M.W. Hofstra, Rudy M. Landsvater, Isabella Ceccherini et al. · Nature · 1994 · 1.2K citations

, , +16

The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis

Charis Eng · JAMA · 1996 · 1K citations

, , +17

1–5 of 1.1K

Authors

5.8K

  1. CE
    Charis Eng

    Cleveland Clinic, United States

    45 publications · 7.7K citations

    32

    h-index

  2. AF
    Alfredo Fusco

    Institute for Experimental Endocrinology and Oncology, Italy

    36 publications · 5.8K citations

    32

    h-index

  3. RM
    Robert M.W. Hofstra

    University of Groningen, Netherlands

    32 publications · 3.6K citations

    26

    h-index

  4. RE
    Rossella Elisei

    University of Pisa, Italy

    28 publications · 4K citations

    25

    h-index

  5. IC
    Isabella Ceccherini

    Istituto Giannina Gaslini, Italy

    29 publications · 3.8K citations

    25

    h-index

1–5 of 5.8K

Institutions

1.5K

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    41 h-index

    220 publications

    21.8K citations

  2. Institute for Experimental Endocrinology and Oncology

    Naples, Italy

    37 h-index

    192 publications

    24.4K citations

  3. University of Cambridge

    Cambridge, United Kingdom

    34 h-index

    170 publications

    48.1K citations

  4. Istituto Giannina Gaslini

    Genoa, Italy

    29 h-index

    179 publications

    23.3K citations

  5. Inserm

    Paris, France

    28 h-index

    155 publications

    17.7K citations

  6. University of Pisa

    Pisa, Italy

    27 h-index

    198 publications

    22.1K citations

  7. Nagoya University

    Nagoya, Japan

    26 h-index

    171 publications

    12.6K citations

  8. Memorial Sloan Kettering Cancer Center

    New York, United States

    26 h-index

    171 publications

    19.4K citations

1–8 of 1.5K

Venues

  1. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 98 publications · 7.9K citations

    52

    h-index

  2. PubMed

    Repository · 69 publications · 5.5K citations

    40

    h-index

  3. Oncogene

    37 publications · 4K citations

    31

    h-index

  4. Thyroid

    35 publications · 1.6K citations

    25

    h-index

  5. Journal of Clinical Oncology

    34 publications · 3.7K citations

    21

    h-index

1–5