Alfredo Fusco

BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas

Marina N. Nikiforova, Edna Teruko Kimura, Manoj Gandhi et al. · The Journal of Clinical Endocrinology & Metabolism · 2003 · 1.1K citations · Full text

Medicine, Genetics, Oncology +17

PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

Michèle Grieco, Massimo Santoro, Maria Teresa Berlingieri et al. · Cell · 1990 · 963 citations

Medicine, Molecular Biology, Molecular Genetics +16

Activation of <i>RET</i> as a Dominant Transforming Gene by Germline Mutations of MEN2A and MEN2B

Massimo Santoro, Francesca Carlomagno, Alfredo Romano et al. · Science · 1995 · 838 citations

Medicine, Genetics, Molecular Genetics +17

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27Kip1 by PKB/Akt-mediated phosphorylation in breast cancer

Giuseppe Viglietto, Maria Letizia Motti, Paola Bruni et al. · Nature Medicine · 2002 · 703 citations

Life Sciences, Cell Biology, Molecular Biology +17

ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases.

Francesca Carlomagno, Donata Vitagliano, Teresa Guida et al. · PubMed · 2002 · 570 citations

Medicine, Oncology, Pharmacology +17