Concepedia

Response Element Recognition

Response Element Recognition is a molecular recognition mechanism in nuclear receptor signaling that specifically identifies and binds to hormone response elements in DNA, thereby enabling selective transcriptional regulation by nuclear receptors.

317

Publications

28.4K

Citations

1.2K

Authors

342

Institutions

Publications per year

2017–2026

10

Parents

Publications

317

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

J�rgen Lehmann, David D. McKee, M. A. Watson et al. · Journal of Clinical Investigation · 1998 · 1.6K citations · Full text

, , +14

LXR, a nuclear receptor that defines a distinct retinoid response pathway.

P J Willy, Kazuhiko Umesono, Estelita S. Ong et al. · Genes & Development · 1995 · 1.1K citations · Full text

, , +17

The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene.

Jonathan Tugwood, Isabelle Issemann, Richard G.W. Anderson et al. · The EMBO Journal · 1992 · 894 citations · Full text

, , +6

The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: How receptors discriminate between their response elements

John W. R. Schwabe, Lynda Chapman, J.T. Finch et al. · Cell · 1993 · 746 citations

, , +16

Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene

Roland Schüle, Kazuhiko Umesono, David J. Mangelsdorf et al. · Cell · 1990 · 520 citations

, , +16

1–5 of 317

Authors

1.2K

  1. FC
    Frank Claessens

    KU Leuven, Belgium

    10 publications · 752 citations

    10

    h-index

  2. WR
    Wilfried Rombauts

    KU Leuven, Belgium

    8 publications · 490 citations

    8

    h-index

  3. GV
    Guy Verrijdt

    KU Leuven, Belgium

    8 publications · 591 citations

    8

    h-index

  4. AM
    Ann M. Nardulli

    University of Illinois Urbana-Champaign, United States

    8 publications · 375 citations

    8

    h-index

  5. AH
    Annemie Haelens

    KU Leuven, Belgium

    7 publications · 547 citations

    7

    h-index

1–5 of 1.2K

Institutions

342

  1. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    45 publications

    5.8K citations

  2. Karolinska Institutet

    Stockholm, Sweden

    11 h-index

    41 publications

    2.3K citations

  3. KU Leuven

    Leuven, Belgium

    10 h-index

    59 publications

    4.3K citations

  4. University of Illinois Urbana-Champaign

    Urbana, United States

    9 h-index

    23 publications

    1.2K citations

  5. Harvard University

    Cambridge, United States

    9 h-index

    31 publications

    3.1K citations

  6. University of California, Davis

    Davis, United States

    8 h-index

    21 publications

    683 citations

  7. Inserm

    Paris, France

    8 h-index

    34 publications

    4.9K citations

  8. University of Rochester

    Rochester, United States

    7 h-index

    16 publications

    452 citations

1–8 of 342

Venues

  1. Journal of Biological Chemistry

    JBC · 51 publications · 4.4K citations

    35

    h-index

  2. Molecular Endocrinology

    42 publications · 3.6K citations

    29

    h-index

  3. Molecular and Cellular Biology

    MCB · 35 publications · 3.6K citations

    26

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 16 publications · 2K citations

    16

    h-index

  5. Nucleic Acids Research

    12 publications · 749 citations

    11

    h-index

1–5