Concepedia

Replication Licensing Control

Replication Licensing Control is a regulatory mechanism in eukaryotic DNA replication that ensures the precise assembly of pre-replicative complexes at origins of replication during the G1 phase, thereby restricting genome duplication to a single round per cell cycle by preventing re-initiation.

77

Publications

7.7K

Citations

372

Authors

156

Institutions

Publications per year

2017–2026

10

Parents

Publications

77

The Cdt1 protein is required to license DNA for replication in fission yeast

Hideo Nishitani, Zoi Lygerou, Takeharu Nishimoto et al. · Nature · 2000 · 467 citations

, , +14

The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome

Alex Kuo, Jikui Song, Peggie Cheung et al. · Nature · 2012 · 351 citations · Full text

, , +13

CDKs Promote DNA Replication Origin Licensing in Human Cells by Protecting Cdc6 from APC/C-Dependent Proteolysis

Niels Mailand, John F.X. Diffley · Cell · 2005 · 338 citations · Full text

, , +14

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

Panagiotis Galanos, Konstantinos Vougas, David Walter et al. · Nature Cell Biology · 2016 · 312 citations · Full text

, , +16

CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing

Weiwei Zhong, Hui Feng, Fernando E. Santiago et al. · Nature · 2003 · 292 citations

, , +14

1–5 of 77

Authors

372

  1. JJ
    J. Julian Blow

    University of Dundee, United Kingdom

    10 publications · 1.1K citations

    10

    h-index

  2. VG
    Vassilis G. Gorgoulis

    National and Kapodistrian University of Athens, Greece

    5 publications · 866 citations

    5

    h-index

  3. ZL
    Zoi Lygerou

    University of Patras, Greece

    5 publications · 993 citations

    5

    h-index

  4. JF
    John F.X. Diffley

    The Francis Crick Institute, United Kingdom

    4 publications · 758 citations

    4

    h-index

  5. ST
    Stavros Taraviras

    University of Patras, Greece

    4 publications · 526 citations

    4

    h-index

1–5 of 372

Institutions

156

  1. University of Dundee

    Dundee, United Kingdom

    8 h-index

    17 publications

    2K citations

  2. National and Kapodistrian University of Athens

    Athens, Greece

    5 h-index

    20 publications

    3.4K citations

  3. Cancer Research UK

    London, United Kingdom

    4 h-index

    9 publications

    1.6K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    15 publications

    780 citations

  5. University of Patras

    Pátrai, Greece

    4 h-index

    23 publications

    2K citations

  6. Kyushu University

    Fukuoka, Japan

    4 h-index

    7 publications

    793 citations

  7. Scripps Research Institute

    San Diego, United States

    4 h-index

    15 publications

    2.4K citations

  8. Wellcome Trust

    London, United Kingdom

    3 h-index

    6 publications

    607 citations

1–8 of 156

Venues

  1. The Journal of Cell Biology

    JCB · 6 publications · 586 citations

    6

    h-index

  2. Journal of Biological Chemistry

    JBC · 6 publications · 593 citations

    6

    h-index

  3. Nature

    5 publications · 1.4K citations

    5

    h-index

  4. Journal of Cell Science

    5 publications · 199 citations

    5

    h-index

  5. Cell Cycle

    5 publications · 120 citations

    5

    h-index

1–5