Concepedia

Repeated-dose Kinetics

Repeated-Dose Kinetics is a subdiscipline of toxicokinetics that characterizes the absorption, distribution, metabolism, and excretion of a chemical following multiple administrations over time, distinguishing it from single-dose kinetics by accounting for cumulative exposure and potential changes in kinetic behavior due to repeated contact.

61

Publications

3.1K

Citations

236

Authors

96

Institutions

Publications per year

2017–2026

5

Parents

Children

Publications

61

TOLERANCE TO BACTERIAL PYROGENS

Paul B. Beeson · The Journal of Experimental Medicine · 1947 · 340 citations · Full text

, , +8

The fate of 2,3,7,8-tetrachlorodibenzo-p-dioxin following single and repeated oral doses to the rat

James Q. Rose, J.C. Ramsey, T.H. Wentzler et al. · Toxicology and Applied Pharmacology · 1976 · 306 citations

, , +9

TOLERANCE TO BACTERIAL PYROGENS

Paul B. Beeson · The Journal of Experimental Medicine · 1947 · 260 citations · Full text

, , +8

Toxicity of WR-2721 administered in single and multiple doses

Morton M. Kligerman, Donna Glover, Andrew T. Turrisi et al. · International Journal of Radiation Oncology*Biology*Physics · 1984 · 127 citations

, , +8

Pharmacokinetics of isotretinoin during repetitive dosing to patients

Romulus K. Brazzell, Floie M. Vane, C. W. Ehmann et al. · European Journal of Clinical Pharmacology · 1983 · 109 citations

, , +11

1–5 of 61

Authors

236

  1. DJ
    David J. Greenblatt

    Tufts University, United States

    5 publications · 133 citations

    5

    h-index

  2. MD
    Marcia D. Allen

    Massachusetts General Hospital, United States

    3 publications · 92 citations

    3

    h-index

  3. WA
    Wayne A. Colburn

    La Roche College, United States

    3 publications · 234 citations

    3

    h-index

  4. HR
    Hermann R. Ochs

    Tufts Medical Center, United States

    2 publications · 41 citations

    2

    h-index

  5. OG
    Odd G. Nilsen

    Norwegian University of Science and Technology, Norway

    2 publications · 96 citations

    2

    h-index

1–5 of 236

Institutions

96

  1. Dow Chemical (United States)

    Midland, United States

    4 h-index

    16 publications

    1.7K citations

  2. Massachusetts General Hospital

    Boston, United States

    3 h-index

    6 publications

    202 citations

  3. University of Tennessee at Knoxville

    Knoxville, United States

    3 h-index

    7 publications

    564 citations

  4. Roche (Switzerland)

    Basel, Switzerland

    3 h-index

    14 publications

    881 citations

  5. Liverpool John Moores University

    Liverpool, United Kingdom

    2 h-index

    8 publications

    196 citations

  6. Norwegian University of Science and Technology

    Trondheim, Norway

    2 h-index

    6 publications

    288 citations

  7. Emory University

    Atlanta, United States

    2 h-index

    2 publications

    600 citations

  8. United States Department of Veterans Affairs

    Washington, United States

    2 h-index

    4 publications

    309 citations

1–8 of 96

Venues

  1. European Journal of Clinical Pharmacology

    7 publications · 235 citations

    7

    h-index

  2. Clinical Pharmacology & Therapeutics

    CPT · 7 publications · 459 citations

    7

    h-index

  3. Toxicology and Applied Pharmacology

    TAAP · 6 publications · 499 citations

    6

    h-index

  4. PubMed

    Repository · 4 publications · 91 citations

    4

    h-index

  5. Pharmacology & Toxicology

    3 publications · 111 citations

    3

    h-index

1–5