Concepedia

Remove Unwanted Variation

Remove Unwanted Variation is a computational method designed to adjust high-dimensional biological data by separating biologically meaningful signals from technical artifacts, batch effects, and other non-biological sources of variation while preserving the underlying biological heterogeneity of interest.

88

Publications

37.2K

Citations

386

Authors

217

Institutions

Publications per year

2017–2026

42

Parents

Publications

88

Nonlinear total variation based noise removal algorithms

L. Rudin, Stanley Osher, Emad Fatemi · Physica D Nonlinear Phenomena · 1992 · 15.7K citations

, , +11

The <tt>sva</tt> package for removing batch effects and other unwanted variation in high-throughput experiments

Jeffrey T. Leek, W. Evan Johnson, Hilary S. Parker et al. · Bioinformatics · 2012 · 6.7K citations · Full text

, , +7

Face recognition using Laplacianfaces

Xiaofei He, Shuicheng Yan, Yuxiao Hu et al. · IEEE Transactions on Pattern Analysis and Machine Intelligence · 2005 · 3.3K citations

, , +15

Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R

Davis J. McCarthy, Kieran R. Campbell, Aaron T. L. Lun et al. · Bioinformatics · 2016 · 2.1K citations · Full text

, , +15

Functional normalization of 450k methylation array data improves replication in large cancer studies

Jean-Philippe Fortin, Aurélie Labbe, Mathieu Lemire et al. · Genome biology · 2014 · 1K citations · Full text

, , +17

1–5 of 88

Authors

386

  1. TP
    Terence P. Speed

    Walter and Eliza Hall Institute of Medical Research, Australia

    14 publications · 1.8K citations

    13

    h-index

  2. JA
    Johann A. Gagnon-Bartsch

    University of Michigan, United States

    8 publications · 1.2K citations

    8

    h-index

  3. KD
    Kasper D. Hansen

    Johns Hopkins University, United States

    4 publications · 1.1K citations

    4

    h-index

  4. SC
    Stephanie C. Hicks

    Johns Hopkins University, United States

    3 publications · 297 citations

    3

    h-index

  5. RA
    Rafael A. Irizarry

    Johns Hopkins University, United States

    3 publications · 297 citations

    3

    h-index

1–5 of 386

Institutions

217

  1. The University of Melbourne

    Melbourne, Australia

    14 h-index

    39 publications

    4.5K citations

  2. Walter and Eliza Hall Institute of Medical Research

    Melbourne, Australia

    12 h-index

    22 publications

    2.4K citations

  3. University of California, Berkeley

    Berkeley, United States

    8 h-index

    22 publications

    2.3K citations

  4. Johns Hopkins University

    Baltimore, United States

    7 h-index

    20 publications

    37K citations

  5. Harvard University

    Cambridge, United States

    5 h-index

    10 publications

    465 citations

  6. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    23 publications

    4.1K citations

  7. Dana-Farber Cancer Institute

    Boston, United States

    4 h-index

    11 publications

    961 citations

  8. University of Chicago

    Chicago, United States

    4 h-index

    7 publications

    6.8K citations

1–8 of 217

Venues

  1. BMC Bioinformatics

    9 publications · 1K citations

    9

    h-index

  2. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 6 publications · 173 citations

    6

    h-index

  3. Bioinformatics

    6 publications · 9.9K citations

    6

    h-index

  4. Briefings in Bioinformatics

    5 publications · 618 citations

    5

    h-index

  5. Biostatistics

    4 publications · 795 citations

    4

    h-index

1–5