Concepedia

Regulatory Element Evolution

Regulatory Element Evolution is the evolutionary process by which noncoding genomic sequences that regulate gene expression acquire functional changes through mutation, selection, and drift, distinguishing it from coding sequence evolution by its focus on the transformation of cis-regulatory modules and transcription factor binding sites that modulate spatial, temporal, and quantitative patterns of gene activity.

188

Publications

15.9K

Citations

931

Authors

356

Institutions

Publications per year

2017–2026

47

Parents

Publications

188

Regulatory evolution of innate immunity through co-option of endogenous retroviruses

Edward B. Chuong, Nels C. Elde, Cédric Feschotte · Science · 2016 · 1.1K citations · Full text

, , +17

Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding

Dominic Schmidt, Michael D. Wilson, Benoît Ballester et al. · Science · 2010 · 736 citations · Full text

, , +17

A RAPID METHOD FOR VIABLE CELL TITRATION AND CLONE PRODUCTION WITH HELA CELLS IN TISSUE CULTURE: THE USE OF X-IRRADIATED CELLS TO SUPPLY CONDITIONING FACTORS

Theodore T. Puck, Philip I. Marcus · Proceedings of the National Academy of Sciences · 1955 · 640 citations · Full text

, , +12

Evolution of the mammalian transcription factor binding repertoire via transposable elements

Guillaume Bourque, Bernard Leong, Vinsensius B. Vega et al. · Genome Research · 2008 · 630 citations · Full text

, , +17

Repeated morphological evolution through cis-regulatory changes in a pleiotropic gene

Benjamin Prud’homme, Nicolas Gompel, Antonis Rokas et al. · Nature · 2006 · 521 citations

, , +12

1–5 of 188

Authors

931

  1. AM
    Alan M Moses

    University of Toronto, Canada

    5 publications · 384 citations

    5

    h-index

  2. TM
    Thomas M. Williams

    University of New Mexico, United States

    5 publications · 680 citations

    5

    h-index

  3. DL
    David L. Stern

    Howard Hughes Medical Institute, United States

    4 publications · 671 citations

    4

    h-index

  4. MB
    Michael B. Eisen

    University of California, Berkeley, United States

    4 publications · 345 citations

    4

    h-index

  5. JF
    John F. McDonald

    Georgia Institute of Technology, United States

    4 publications · 207 citations

    4

    h-index

1–5 of 931

Institutions

356

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    12 h-index

    36 publications

    7.8K citations

  2. University of Chicago

    Chicago, United States

    9 h-index

    29 publications

    2.5K citations

  3. University of California, Berkeley

    Berkeley, United States

    8 h-index

    22 publications

    2.1K citations

  4. Cornell University

    Ithaca, United States

    8 h-index

    31 publications

    3.1K citations

  5. University of Cambridge

    Cambridge, United Kingdom

    7 h-index

    16 publications

    2.3K citations

  6. Duke University

    Durham, United States

    6 h-index

    11 publications

    356 citations

  7. University of Pennsylvania

    Philadelphia, United States

    6 h-index

    20 publications

    3.4K citations

  8. University of Illinois Urbana-Champaign

    Urbana, United States

    6 h-index

    19 publications

    749 citations

1–8 of 356

Venues

  1. Molecular Biology and Evolution

    MBE · 22 publications · 1.9K citations

    20

    h-index

  2. Genome Research

    GR · 14 publications · 2K citations

    14

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 16 publications · 1.7K citations

    14

    h-index

  4. Science

    9 publications · 2.8K citations

    9

    h-index

  5. PLoS Genetics

    7 publications · 428 citations

    7

    h-index

1–5