Concepedia

Rag1 Deficiency

RAG1 Deficiency is a monogenic form of autosomal recessive severe combined immunodeficiency characterized by impaired V(D)J recombination due to pathogenic variants in the RAG1 gene, leading to defective T and B lymphocyte development.

210

Publications

16.5K

Citations

1.7K

Authors

604

Institutions

Publications per year

2017–2026

64

Parents

Publications

210

RAG-1-deficient mice have no mature B and T lymphocytes

Peter Mombaerts, John Iacomini, Randall S. Johnson et al. · Cell · 1992 · 2.9K citations

, , +13

RAG Mutations in Human B Cell-Negative SCID

Klaus Schwarz, George H. Gauss, Leopold Ludwig et al. · Science · 1996 · 532 citations

, , +17

Bcl-2 Can Rescue T Lymphocyte Development in Interleukin-7 Receptor–Deficient Mice but Not in Mutant rag-1 −/− Mice

Eugene Maraskovsky, Lorraine A. O’Reilly, Mark Teepe et al. · Cell · 1997 · 497 citations · Full text

, , +11

Target-Selected Inactivation of the Zebrafish <i>rag1</i> Gene

Erno Wienholds, Stefan Schulte‐Merker, Brigitte Walderich et al. · Science · 2002 · 402 citations

, , +15

The IL-6R α chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo

Aysefa Doganci, Tatjana Eigenbrod, Norbert Krug et al. · Journal of Clinical Investigation · 2005 · 334 citations · Full text

, , +17

1–5 of 210

Authors

1.7K

  1. LD
    Luigi D. Notarangelo

    National Institute of Allergy and Infectious Diseases, United States

    13 publications · 466 citations

    13

    h-index

  2. AV
    Anna Villa

    Institute of Genetic and Biomedical Research, Italy

    9 publications · 265 citations

    9

    h-index

  3. MV
    Mirjam van der Burg

    Erasmus MC, Netherlands

    6 publications · 261 citations

    6

    h-index

  4. MW
    Micheline Wésolowski‐Louvel

    Université Claude Bernard Lyon 1, France

    6 publications · 319 citations

    6

    h-index

  5. MC
    Marina Cavazzana

    Inserm, France

    6 publications · 498 citations

    6

    h-index

1–5 of 1.7K

Institutions

604

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    16 h-index

    40 publications

    12.5K citations

  2. National Institutes of Health

    Bethesda, United States

    14 h-index

    55 publications

    3.4K citations

  3. Harvard University

    Cambridge, United States

    13 h-index

    37 publications

    4.5K citations

  4. Boston Children's Hospital

    Boston, United States

    13 h-index

    46 publications

    1.6K citations

  5. Inserm

    Paris, France

    10 h-index

    47 publications

    3.4K citations

  6. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    9 h-index

    36 publications

    1.4K citations

  7. Université Paris Cité

    Paris, France

    8 h-index

    47 publications

    5K citations

  8. Erasmus MC

    Rotterdam, The Netherlands

    7 h-index

    21 publications

    1.4K citations

1–8 of 604

Venues

  1. Blood

    16 publications · 1.2K citations

    16

    h-index

  2. The Journal of Immunology

    JI · 11 publications · 574 citations

    11

    h-index

  3. Journal of Clinical Investigation

    JCI · 8 publications · 1.6K citations

    8

    h-index

  4. PLoS ONE

    8 publications · 299 citations

    8

    h-index

  5. Journal of Clinical Immunology

    7 publications · 231 citations

    7

    h-index

1–5