Concepedia

Rab7-mediated Tethering

Rab7-Mediated Tethering is a molecular mechanism in the autophagic pathway wherein the small GTPase Rab7 facilitates the initial docking of autophagosomes to lysosomes by recruiting tethering effectors that bridge the two organelles prior to membrane fusion.

32

Publications

3.8K

Citations

177

Authors

75

Institutions

Publications per year

2017–2026

9

Parents

Publications

32

Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

Yvette C. Wong, Daniel Ysselstein, Dimitri Krainc · Nature · 2018 · 859 citations · Full text

, , +16

RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk

David MacLeod, Hervé Rhinn, Tomoki Kuwahara et al. · Neuron · 2013 · 536 citations · Full text

, , +16

Phagosomes Fuse with Late Endosomes and/or Lysosomes by Extension of Membrane Protrusions along Microtubules: Role of Rab7 and RILP

Rene E. Harrison, Cecilia Bucci, Otília V. Vieira et al. · Molecular and Cellular Biology · 2003 · 468 citations · Full text

, , +17

The Mon1-Ccz1 Complex Is the GEF of the Late Endosomal Rab7 Homolog Ypt7

Mirjana Nordmann, Margarita Cabrera, Angela Perz et al. · Current Biology · 2010 · 405 citations · Full text

, , +8

Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy

Koji Yamano, Adam I. Fogel, Chunxin Wang et al. · eLife · 2014 · 307 citations · Full text

, , +16

1–5 of 32

Authors

177

  1. CU
    Christian Ungermann

    Osnabrück University, Germany

    6 publications · 688 citations

    6

    h-index

  2. CB
    Cecilia Bucci

    University of Salento, Italy

    4 publications · 581 citations

    4

    h-index

  3. JL
    Jens Lachmann

    Osnabrück University, Germany

    3 publications · 113 citations

    3

    h-index

  4. LL
    Lars Langemeyer

    Osnabrück University, Germany

    2 publications · 170 citations

    2

    h-index

  5. DM
    David MacLeod

    University of Bristol, United Kingdom

    2 publications · 562 citations

    2

    h-index

1–5 of 177

Institutions

75

  1. Osnabrück University

    Osnabrück, Germany

    6 h-index

    26 publications

    4K citations

  2. National Institutes of Health

    Bethesda, United States

    3 h-index

    16 publications

    1.7K citations

  3. University of Salento

    Lecce, Italy

    3 h-index

    10 publications

    914 citations

  4. Northwestern University

    Evanston, United States

    2 h-index

    11 publications

    2.8K citations

  5. Istituto Nazionale di Fisica Nucleare, Sezione di Lecce

    Lecce, Italy

    2 h-index

    5 publications

    624 citations

  6. Inserm

    Paris, France

    2 h-index

    9 publications

    442 citations

  7. VIB-KU Leuven Center for Brain & Disease Research

    Leuven, Belgium

    1 h-index

    1 publications

    28 citations

  8. Taipei Municipal YangMing Hospital

    Taipei, Taiwan

    1 h-index

    1 publications

    32 citations

1–8 of 75

Venues

  1. Biochemical and Biophysical Research Communications

    BBRC · 4 publications · 136 citations

    4

    h-index

  2. Neuron

    2 publications · 562 citations

    2

    h-index

  3. Small GTPases

    2 publications · 43 citations

    2

    h-index

  4. Molecular Biology of the Cell

    MBC · 2 publications · 207 citations

    2

    h-index

  5. eLife

    2 publications · 412 citations

    2

    h-index

1–5