PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

Lesley A. Kane, Michael Lazarou, Adam I. Fogel, +5

The Journal of Cell Biology

Cell AutophagyMitophagySelective AutophagySignal TransductionProtein Function +12

PINK1 is degraded through the N-end rule pathway

Koji Yamano, Richard J. Youle

Autophagy

Genome InstabilityMitophagyMitochondrial FunctionMedicineParkinson Disease +9

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

Samuel A. Hasson, Lesley A. Kane, Koji Yamano, +9

Nature

Transcriptional RegulationMitophagyFunctional GenomicsGeneticsParkin Upstream +8

Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy

Koji Yamano, Adam I. Fogel, Chunxin Wang, +2

eLife

Cell AutophagyMitophagyAutophagosome MorphogenesisSignal TransductionMitochondrial Function +12

Mutations in Fis1 disrupt orderly disposal of defective mitochondria

Qinfang Shen, Koji Yamano, Brian Head, +7

Molecular Biology of the Cell

Mitochondrial Fission ComplexMitochondrial FunctionMitochondrial DynamicMedicineGenetics +11

Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy

Koji Yamano, Reika Kikuchi, Waka Kojima, +8

The Journal of Cell Biology

MitophagyGeneticsMitochondrial UbiquitinationMolecular BiologyCell Death +17

Endosomal Rab cycles regulate Parkin-mediated mitophagy

Koji Yamano, Chunxin Wang, Shireen A. Sarraf, +9

eLife

Cargo UbiquitinationCell AutophagyMitophagyNeurodegenerative DiseasesSignal Transduction +13

Tom20 and Tom22 Share the Common Signal Recognition Pathway in Mitochondrial Protein Import

Koji Yamano, Yoh-ichi Yatsukawa, Masatoshi Esaki, +3

Journal of Biological Chemistry

Mitochondrial DynamicMitochondrial BiogenesisMitochondrial FunctionBiochemistryNatural Sciences +13

Tam41 Is a CDP-Diacylglycerol Synthase Required for Cardiolipin Biosynthesis in Mitochondria

Yasushi Tamura, Yoshihiro Harada, Shuh‐ichi Nishikawa, +9

Cell Metabolism

BiosynthesisOxysterolMitochondrial FunctionBiochemistryNatural Sciences +4

Tim23–Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import

Yasushi Tamura, Yoshihiro Harada, Takuya Shiota, +6

The Journal of Cell Biology

Signal TransductionMitochondrial FunctionOuter MembraneNatural SciencesMitochondrial Membrane +12