Concepedia

R-loop Resolution

R-Loop Resolution is a molecular mechanism within the replication stress response that specifically disassembles RNA-DNA hybrid structures formed co-transcriptionally, thereby preventing transcription-replication conflicts and maintaining genome stability.

109

Publications

9.9K

Citations

705

Authors

261

Institutions

Publications per year

2017–2026

84

Parents

Publications

109

Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses

Stephan Hamperl, M Bocek, Joshua C. Saldivar et al. · Cell · 2017 · 677 citations · Full text

, , +12

Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis

Aziz El Hage, Sarah L. French, Ann L. Beyer et al. · Genes & Development · 2010 · 416 citations · Full text

, , +15

Yeast Sen1 Helicase Protects the Genome from Transcription-Associated Instability

Hannah E. Mischo, Belén Gómez‐González, Pawel Grzechnik et al. · Molecular Cell · 2011 · 349 citations · Full text

, , +15

High-resolution, strand-specific R-loop mapping via S9.6-based DNA–RNA immunoprecipitation and high-throughput sequencing

Lionel A. Sanz, Frédéric Chédin · Nature Protocols · 2019 · 314 citations · Full text

, , +8

Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1

Hai Dang Nguyen, Tribhuwan Yadav, Sumanprava Giri et al. · Molecular Cell · 2017 · 272 citations · Full text

, , +14

1–5 of 109

Authors

705

  1. AA
    Andrés Aguilera

    Universidad de Sevilla, Spain

    7 publications · 1.1K citations

    7

    h-index

  2. JM
    Jean‐Yves Masson

    Université Laval, Canada

    6 publications · 585 citations

    6

    h-index

  3. MD
    Marc Drolet

    Université de Montréal, Canada

    5 publications · 273 citations

    5

    h-index

  4. FC
    Frédéric Chédin

    University of California, Davis, United States

    5 publications · 744 citations

    5

    h-index

  5. SY
    Sofiane Y. Mersaoui

    Université Laval, Canada

    4 publications · 434 citations

    4

    h-index

1–5 of 705

Institutions

261

  1. Universidad de Sevilla

    Seville, Spain

    7 h-index

    32 publications

    4.7K citations

  2. Centro Andaluz de Biología Molecular y Medicina Regenerativa

    Seville, Spain

    7 h-index

    31 publications

    4.5K citations

  3. Université de Montréal

    Montreal, Canada

    7 h-index

    26 publications

    1.1K citations

  4. Université Laval

    Québec, Canada

    6 h-index

    16 publications

    1.7K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    11 publications

    1.1K citations

  6. McGill University

    Montreal, Canada

    5 h-index

    17 publications

    1.5K citations

  7. Harvard University

    Cambridge, United States

    5 h-index

    27 publications

    4.6K citations

  8. Universidad Pablo de Olavide

    Seville, Spain

    4 h-index

    18 publications

    2.1K citations

1–8 of 261

Venues

  1. Nucleic Acids Research

    15 publications · 846 citations

    15

    h-index

  2. Nature Communications

    9 publications · 876 citations

    8

    h-index

  3. The EMBO Journal

    7 publications · 771 citations

    7

    h-index

  4. Cell Reports

    7 publications · 519 citations

    7

    h-index

  5. Molecular Cell

    6 publications · 1.1K citations

    6

    h-index

1–5