Concepedia

Proteolytic Remodeling

Proteolytic Remodeling is a biological process in which targeted proteolytic cleavage of specific peptide bonds within a protein or protein complex leads to structural and functional alterations that regulate molecular activity, localization, or interactions within a cellular context.

277

Publications

24.6K

Citations

1.6K

Authors

518

Institutions

Publications per year

2017–2026

47

Parents

Publications

277

Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: Engineering cell-invasion characteristics

Matthias P. Lütolf, Janelle L. Lauer‐Fields, Hugo G. Schmoekel et al. · Proceedings of the National Academy of Sciences · 2003 · 1.5K citations · Full text

, , +17

Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

Katarina Wolf, Yi Wu, Yueying Liu et al. · Nature Cell Biology · 2007 · 995 citations · Full text

, , +14

Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: Structure-based mechanism of conversion

Cristofer Enroth, B.T. Eger, Ken Okamoto et al. · Proceedings of the National Academy of Sciences · 2000 · 718 citations · Full text

, , +15

Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion

Qin Yu, Ivan Stamenkovic · Genes & Development · 1999 · 705 citations · Full text

, , +17

Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP

Farideh Sabeh, Ichiro Ota, Kenn Holmbeck et al. · The Journal of Cell Biology · 2004 · 579 citations · Full text

, , +17

1–5 of 277

Authors

1.6K

  1. BF
    Bonnie F. Sloane

    Wayne State University, United States

    4 publications · 254 citations

    4

    h-index

  2. MS
    Mansoureh Sameni

    Wayne State University, United States

    3 publications · 151 citations

    3

    h-index

  3. JD
    Julie Dosescu

    Wayne State University, United States

    3 publications · 151 citations

    3

    h-index

  4. JA
    Jeffrey A. Hubbell

    École Polytechnique Fédérale de Lausanne, Switzerland

    3 publications · 2.2K citations

    3

    h-index

  5. PK
    Peter‐M. Kloetzel

    Charité - Universitätsmedizin Berlin, Germany

    3 publications · 237 citations

    3

    h-index

1–5 of 1.6K

Institutions

518

  1. Harvard University

    Cambridge, United States

    17 h-index

    73 publications

    12.3K citations

  2. Inserm

    Paris, France

    14 h-index

    51 publications

    3.8K citations

  3. National Institutes of Health

    Bethesda, United States

    11 h-index

    50 publications

    3K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    28 publications

    2K citations

  5. Massachusetts General Hospital

    Boston, United States

    8 h-index

    30 publications

    4.8K citations

  6. Wayne State University

    Detroit, United States

    7 h-index

    32 publications

    2.9K citations

  7. National Cancer Institute

    Bethesda, United States

    6 h-index

    30 publications

    1.4K citations

  8. Hospital for Sick Children

    Toronto, Canada

    6 h-index

    17 publications

    2.5K citations

1–8 of 518

Venues

  1. Journal of Biological Chemistry

    JBC · 26 publications · 3.3K citations

    25

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 14 publications · 4K citations

    13

    h-index

  3. PubMed

    Repository · 13 publications · 879 citations

    12

    h-index

  4. Biochemical Journal

    BJ · 9 publications · 346 citations

    9

    h-index

  5. The Journal of Cell Biology

    JCB · 8 publications · 1.2K citations

    8

    h-index

1–5