Concepedia

Proteolytic Processing Of Interaction Partners

Proteolytic Processing of Interaction Partners is a post-translational regulatory mechanism in which the cleavage of one or more interaction partners by proteases modulates protein–protein interactions through structural or functional alterations of the binding interfaces.

44

Publications

2.7K

Citations

208

Authors

84

Institutions

Publications per year

2017–2026

8

Parents

Publications

44

Human C4-binding protein. II. Role in proteolysis of C4b by C3b-inactivator.

T Fujita, Irma Gigli, Victor Nussenzweig · The Journal of Experimental Medicine · 1978 · 283 citations · Full text

, , +12

A Novel Role for FAK as a Protease-Targeting Adaptor Protein

Neil O. Carragher, Mike‐Andrew Westhoff, Valerie J. Fincham et al. · Current Biology · 2003 · 194 citations · Full text

, , +13

Proteolytic processing of the Drosophila Spätzle protein by Easter generates a dimeric NGF-like molecule with ventralising activity

Yvonne DeLotto, Robert DeLotto · Mechanisms of Development · 1998 · 186 citations

, , +12

Neutrophil Elastase Acts as a Biased Agonist for Proteinase-activated Receptor-2 (PAR2)

Rithwik Ramachandran, Koichiro Mihara, Hyunjae Chung et al. · Journal of Biological Chemistry · 2011 · 170 citations · Full text

, , +12

The role of C4-binding protein and {beta }1H in proteolysis of C4b and C3b

T Fujita, Victor Nussenzweig · The Journal of Experimental Medicine · 1979 · 149 citations · Full text

, , +14

1–5 of 44

Authors

208

  1. SR
    Stefan Rose‐John

    Christian-Albrechts-Universität zu Kiel, Germany

    2 publications · 153 citations

    2

    h-index

  2. VN
    Victor Nussenzweig

    New York University, United States

    2 publications · 432 citations

    2

    h-index

  3. TF
    T Fujita

    Saga Medical School Hospital, Japan

    2 publications · 432 citations

    2

    h-index

  4. CG
    Christoph Garbers

    Christian-Albrechts-Universität zu Kiel, Germany

    2 publications · 153 citations

    2

    h-index

  5. BR
    Björn Rabe

    Christian-Albrechts-Universität zu Kiel, Germany

    2 publications · 153 citations

    2

    h-index

1–5 of 208

Institutions

84

  1. Christian-Albrechts-Universität zu Kiel

    Kiel, Germany

    3 h-index

    27 publications

    1.9K citations

  2. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    8 publications

    651 citations

  3. Max Planck Society

    Munich, Germany

    2 h-index

    3 publications

    256 citations

  4. New York University

    New York, United States

    2 h-index

    5 publications

    641 citations

  5. University of Calgary

    Calgary, Canada

    2 h-index

    7 publications

    1K citations

  6. University of Pittsburgh

    Pittsburgh, United States

    2 h-index

    3 publications

    67 citations

  7. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    4 publications

    425 citations

  8. Baylor College of Medicine

    Houston, United States

    2 h-index

    4 publications

    106 citations

1–8 of 84

Venues

  1. Journal of Biological Chemistry

    JBC · 4 publications · 296 citations

    4

    h-index

  2. The Journal of Experimental Medicine

    3 publications · 520 citations

    3

    h-index

  3. Journal of Molecular Biology

    JMB · 2 publications · 45 citations

    2

    h-index

  4. Scientific Reports

    2 publications · 153 citations

    2

    h-index

  5. Current Biology

    2 publications · 265 citations

    2

    h-index

1–5