Concepedia

Protein-binding Libraries

Protein-Binding Libraries is a type of dynamic combinatoratorial library constructed from a set of interchanging molecular building blocks under thermodynamic control, in which the target protein selectively amplifies and stabilizes high-affinity ligands through binding interactions, thereby enriching the library composition toward biologically active compounds.

59

Publications

4.1K

Citations

345

Authors

99

Institutions

Publications per year

2017–2026

13

Parents

Publications

59

High-affinity binders selected from designed ankyrin repeat protein libraries

Hans Binz, Patrick Amstutz, A. Kohl et al. · Nature Biotechnology · 2004 · 667 citations

, , +14

Binding proteins selected from combinatorial libraries of an α-helical bacterial receptor domain

Karin Nord, Elin Gunneriusson, Jenny Ringdahl et al. · Nature Biotechnology · 1997 · 657 citations

, , +14

A combinatorial library of an α-helical bacterial receptor domain

Karin Nord, Joakim Nilsson, Björn Nilsson et al. · Protein Engineering Design and Selection · 1995 · 287 citations

, , +17

Isolation of the new antigen receptor from wobbegong sharks, and use as a scaffold for the display of protein loop libraries

Stewart D. Nuttall, Usha V. Krishnan, Meghan Hattarki et al. · Molecular Immunology · 2001 · 157 citations

, , +14

A systematic survey of the Cys2His2 zinc finger DNA-binding landscape

Anton V. Persikov, Joshua L. Wetzel, Elizabeth F. Rowland et al. · Nucleic Acids Research · 2015 · 112 citations · Full text

, , +17

1–5 of 59

Authors

345

  1. PN
    Per‐Åke Nygren

    KTH Royal Institute of Technology, Sweden

    4 publications · 1.1K citations

    4

    h-index

  2. KN
    Karin Nord

    KTH Royal Institute of Technology, Sweden

    3 publications · 1K citations

    3

    h-index

  3. AP
    Andreas Plückthun

    University of Zurich, Switzerland

    3 publications · 730 citations

    3

    h-index

  4. MU
    Mathias Uhlén

    KTH Royal Institute of Technology, Sweden

    3 publications · 1K citations

    3

    h-index

  5. WC
    Wenying Chai

    University of Kansas, United States

    2 publications · 62 citations

    2

    h-index

1–5 of 345

Institutions

99

  1. University of Zurich

    Zurich, Switzerland

    6 h-index

    36 publications

    6.8K citations

  2. KTH Royal Institute of Technology

    Stockholm, Sweden

    5 h-index

    13 publications

    4.6K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    21 publications

    623 citations

  4. Philipps University of Marburg

    Marburg, Germany

    2 h-index

    11 publications

    407 citations

  5. Princeton University

    Princeton, United States

    2 h-index

    10 publications

    859 citations

  6. University of Groningen

    Groningen, The Netherlands

    2 h-index

    11 publications

    581 citations

  7. ETH Zurich

    Zurich, Switzerland

    2 h-index

    8 publications

    608 citations

  8. Scripps Research Institute

    San Diego, United States

    2 h-index

    12 publications

    388 citations

1–8 of 99

Venues

  1. Angewandte Chemie International Edition

    4 publications · 130 citations

    4

    h-index

  2. Biochemistry

    3 publications · 175 citations

    3

    h-index

  3. PLoS ONE

    3 publications · 79 citations

    3

    h-index

  4. Chemistry - A European Journal

    2 publications · 124 citations

    2

    h-index

  5. ChemBioChem

    2 publications · 76 citations

    2

    h-index

1–5