Concepedia

Protein Surface Charge Engineering

Protein Surface Charge Engineering is a protein engineering strategy that involves the rational modification of ionizable amino acid residues on a protein's surface to alter its electrostatic properties, thereby influencing solubility, stability, and molecular interactions under specific environmental conditions.

33

Publications

1.9K

Citations

185

Authors

61

Institutions

Publications per year

2017–2026

17

Parents

Publications

33

A Convenient and Versatile Amino‐Acid‐Boosted Biomimetic Strategy for the Nondestructive Encapsulation of Biomacromolecules within Metal–Organic Frameworks

Guosheng Chen, Siming Huang, Xiaoxue Kou et al. · Angewandte Chemie International Edition · 2018 · 333 citations

, , +17

Rational modification of enzyme catalysis by engineering surface charge

Alan J. Russell, Alan R. Fersht · Nature · 1987 · 331 citations

, , +16

Prediction of electrostatic effects of engineering of protein charges

Michael J.E. Sternberg, Fiona R. F. Hayes, Alan J. Russell et al. · Nature · 1987 · 218 citations

, , +14

Surface charge engineering of nanosized CuS <i>via</i> acidic amino acid modification enables high peroxidase-mimicking activity at neutral pH for one-pot detection of glucose

Xiangheng Niu, Xuechao Xu, Xin Li et al. · Chemical Communications · 2018 · 113 citations

, , +15

Improvement of the acid resistance, catalytic efficiency, and thermostability of nattokinase by multisite‐directed mutagenesis

Zhongmei Liu, Han Zhao, Laichuang Han et al. · Biotechnology and Bioengineering · 2019 · 60 citations

, , +13

1–5 of 33

Authors

185

  1. AJ
    Alan J. Russell

    University of Pittsburgh, United States

    4 publications · 589 citations

    4

    h-index

  2. SH
    Siming Huang

    Sun Yat-sen University, China

    2 publications · 355 citations

    2

    h-index

  3. SH
    Shuyao Huang

    Sun Yat-sen University, China

    2 publications · 355 citations

    2

    h-index

  4. GO
    Gangfeng Ouyang

    Sun Yat-sen University, China

    2 publications · 355 citations

    2

    h-index

  5. SW
    Songbo Wei

    Sun Yat-sen University, China

    2 publications · 355 citations

    2

    h-index

1–5 of 185

Institutions

61

  1. Jiangnan University

    Wuxi, China

    4 h-index

    26 publications

    960 citations

  2. Sun Yat-sen University

    Guangzhou, China

    3 h-index

    19 publications

    3.2K citations

  3. Sun Yat-sen Memorial Hospital

    Guangzhou, China

    2 h-index

    8 publications

    1.4K citations

  4. Imperial College London

    London, United Kingdom

    2 h-index

    5 publications

    1.3K citations

  5. Pulmonary and Critical Care Associates

    Jacksonville, United States

    1 h-index

    3 publications

    84 citations

  6. Universidad de Granada

    Granada, Spain

    1 h-index

    5 publications

    150 citations

  7. Birkbeck, University of London

    London, United Kingdom

    1 h-index

    2 publications

    436 citations

  8. Parque Tecnológico de la Salud

    Granada, Spain

    1 h-index

    4 publications

    120 citations

1–8 of 61

Venues

  1. 3

    h-index

  2. Protein Engineering Design and Selection

    PEDS · 3 publications · 105 citations

    3

    h-index

  3. Nature

    2 publications · 549 citations

    2

    h-index

  4. Biotechnology and Bioengineering

    2 publications · 72 citations

    2

    h-index

  5. 2

    h-index

1–5