Laichuang Han

Improvement of the acid resistance, catalytic efficiency, and thermostability of nattokinase by multisite‐directed mutagenesis

Zhongmei Liu, Han Zhao, Laichuang Han et al. · Biotechnology and Bioengineering · 2019 · 58 citations

Development of a novel strategy for robust synthetic bacterial promoters based on a stepwise evolution targeting the spacer region of the core promoter in Bacillus subtilis

Laichuang Han, Wenjing Cui, Feiya Suo et al. · Microbial Cell Factories · 2019 · 56 citations · Full text

Counteraction of stability-activity trade-off of Nattokinase through flexible region shifting

Jie Luo, Chenshuo Song, Wenjing Cui et al. · Food Chemistry · 2023 · 54 citations

Engineering, Biochemistry, Biotechnology +3

Insight into the broadened substrate scope of nitrile hydratase by static and dynamic structure analysis

Dong Ma, Zhongyi Cheng, Laichuang Han et al. · Chemical Science · 2022 · 43 citations · Full text

Engineering, Aldo-keto Reductase, Substrate Scope +19

Engineering an inducible gene expression system for Bacillus subtilis from a strong constitutive promoter and a theophylline-activated synthetic riboswitch

Wenjing Cui, Laichuang Han, Jintao Cheng et al. · Microbial Cell Factories · 2016 · 42 citations · Full text