Concepedia

Protein Interface Design

Protein Interface Design is a computational and experimental methodology within protein engineering that specifically focuses on the rational modification or de novo creation of interaction surfaces between proteins to achieve desired binding affinities, specificities, and functional outcomes.

117

Publications

8.3K

Citations

583

Authors

219

Institutions

Publications per year

2017–2026

28

Parents

Publications

117

Shape Complementarity at Protein/Protein Interfaces

Michael C. Lawrence, Peter M. Colman · Journal of Molecular Biology · 1993 · 1.2K citations

, , +14

Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

Sarel J. Fleishman, Timothy A. Whitehead, Damian C. Ekiert et al. · Science · 2011 · 597 citations

, , +17

A Dissection of Specific and Non-specific Protein–Protein Interfaces

Ranjit Prasad Bahadur, Pinak Chakrabarti, Françis Rodier et al. · Journal of Molecular Biology · 2004 · 449 citations

, , +12

Rational design of faster associating and tighter binding protein complexes.

Gideon Schreiber, Tzvia Selzer, Shira Albeck · Nature Structural Biology · 2000 · 304 citations

, , +16

Assessing Helical Protein Interfaces for Inhibitor Design

Brooke N. Bullock, Andrea L. Jochim, Paramjit S. Arora · Journal of the American Chemical Society · 2011 · 294 citations · Full text

, , +17

1–5 of 117

Authors

583

  1. DB
    David Baker

    University of Washington, United States

    10 publications · 1.3K citations

    10

    h-index

  2. BK
    Brian Kuhlman

    University of North Carolina at Chapel Hill, United States

    9 publications · 799 citations

    9

    h-index

  3. GS
    Gideon Schreiber

    Weizmann Institute of Science, Israel

    5 publications · 762 citations

    5

    h-index

  4. AK
    Akiko Koide

    University of Chicago, United States

    4 publications · 425 citations

    4

    h-index

  5. TO
    Todd O. Yeates

    University of California, Los Angeles, United States

    4 publications · 81 citations

    4

    h-index

1–5 of 583

Institutions

219

  1. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    10 h-index

    37 publications

    2.9K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    13 publications

    1.9K citations

  3. University of Washington

    Seattle, United States

    10 h-index

    55 publications

    5.8K citations

  4. Weizmann Institute of Science

    Rehovot, Israel

    5 h-index

    25 publications

    3.6K citations

  5. University of Chicago

    Chicago, United States

    4 h-index

    20 publications

    2.1K citations

  6. Kyoto University

    Kyoto, Japan

    4 h-index

    11 publications

    263 citations

  7. Lawrence Berkeley National Laboratory

    Berkeley, United States

    4 h-index

    5 publications

    175 citations

  8. University of California, Los Angeles

    Los Angeles, United States

    3 h-index

    9 publications

    194 citations

1–8 of 219

Venues

  1. Journal of Molecular Biology

    JMB · 15 publications · 1.9K citations

    15

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 15 publications · 1.3K citations

    15

    h-index

  3. Journal of the American Chemical Society

    JACS · 7 publications · 484 citations

    7

    h-index

  4. PLoS ONE

    4 publications · 155 citations

    4

    h-index

  5. Protein Engineering Design and Selection

    PEDS · 4 publications · 274 citations

    4

    h-index

1–5